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    ctdsplb CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like b [ Danio rerio (zebrafish) ]

    Gene ID: 767676, updated on 27-Dec-2024

    Summary

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    Official Symbol
    ctdsplbprovided by ZNC
    Official Full Name
    CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060929-488
    See related
    Ensembl:ENSDARG00000062116 AllianceGenome:ZFIN:ZDB-GENE-060929-488
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fd18d04; zgc:154102
    Summary
    Predicted to enable RNA polymerase II CTD heptapeptide repeat phosphatase activity and myosin phosphatase activity. Orthologous to human CTDSPL (CTD small phosphatase like). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See ctdsplb in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (21356303..21383393)
    105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (21697275..21725331)

    Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene kelch-like family member 40a Neighboring gene hedgehog acyltransferase like, a Neighboring gene microRNA 26a-2 Neighboring gene phospholipase C, delta 1b Neighboring gene uncharacterized LOC108179685 Neighboring gene AFG3-like AAA ATPase 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC154102

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA polymerase II CTD heptapeptide repeat phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables myosin phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like b
    NP_001070083.1
    XP_005163418.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001076615.1 → NP_001070083.1  CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like b

      See identical proteins and their annotated locations for NP_001070083.1

      Status: PROVISIONAL

      Source sequence(s)
      BC124542
      UniProtKB/TrEMBL
      Q08BV3
      Related
      ENSDARP00000141942.2, ENSDART00000171397.2
      Conserved Domains (2) summary
      COG5190
      Location:69 → 261
      FCP1; TFIIF-interacting CTD phosphatase, includes NLI-interacting factor [Transcription]
      TIGR02251
      Location:96 → 255
      HIF-SF_euk; Dullard-like phosphatase domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007113.7 Reference GRCz11 Primary Assembly

      Range
      21356303..21383393
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005163361.5 → XP_005163418.1  CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like b isoform X1

      UniProtKB/TrEMBL
      A0A8M2BAS3
      Conserved Domains (2) summary
      COG5190
      Location:93 → 272
      FCP1; TFIIF-interacting CTD phosphatase, includes NLI-interacting factor [Transcription]
      TIGR02251
      Location:107 → 266
      HIF-SF_euk; Dullard-like phosphatase domain
    Nucleotide Protein Strain
    Heading Accession and Version

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