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    Protein with RING/U-box and TRAF-like domain [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818798, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Protein with RING/U-box and TRAF-like domain
    Primary source
    TAIR:AT2G41980
    Locus tag
    AT2G41980
    See related
    Araport:AT2G41980
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T6D20.13; T6D20_13
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    5
    Sequence:
    Chromosome: 2; NC_003071.7 (17523071..17526126, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene ncRNA Neighboring gene Protein kinase superfamily protein Neighboring gene late embryogenesis abundant protein Neighboring gene plant EC metallothionein family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. 14-3-3 proteins contribute to autophagy by modulating SINAT-mediated degradation of ATG13. Qi H, et al. Plant Cell, 2022 Nov 29. PMID 36053201, Free PMC Article
    2. SINAT E3 ligases regulate the stability of the ESCRT component FREE1 in response to iron deficiency in plants. Xiao Z, et al. J Integr Plant Biol, 2020 Sep. PMID 32786047
    3. The tumor necrosis factor receptor-associated factor (TRAF)-like family protein SEVEN IN ABSENTIA 2 (SINA2) promotes drought tolerance in an ABA-dependent manner in Arabidopsis. Bao Y, et al. New Phytol, 2014 Apr. PMID 24350984
    4. TRAF Family Proteins Regulate Autophagy Dynamics by Modulating AUTOPHAGY PROTEIN6 Stability in Arabidopsis. Qi H, et al. Plant Cell, 2017 Apr. PMID 28351989, Free PMC Article
    5. The wavy growth 3 E3 ligase family controls the gravitropic response in Arabidopsis roots. Sakai T, et al. Plant J, 2012 Apr. PMID 22122664

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    NM_129762.6

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein ubiquitination IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within protein ubiquitination IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    involved_in regulation of autophagosome assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in ubiquitin-dependent protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Protein with RING/U-box and TRAF-like domain
    NP_181729.1
    • Protein with RING/U-box and TRAF-like domains; FUNCTIONS IN: ubiquitin-protein ligase activity, zinc ion binding; INVOLVED IN: multicellular organismal development, ubiquitin-dependent protein catabolic process, protein ubiquitination; LOCATED IN: nucleus; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: TRAF-like (InterPro:IPR008974), Seven-in-absentia protein, TRAF-like domain (InterPro:IPR018121), Zinc finger, SIAH-type (InterPro:IPR013010), Zinc finger, RING-type (InterPro:IPR001841), Seven In Absentia Homolog-type (InterPro:IPR013323), Seven-in-absentia protein, sina (InterPro:IPR004162), TRAF-type (InterPro:IPR013322); BEST Arabidopsis thaliana protein match is: seven in absentia of Arabidopsis 2 (TAIR:AT3G58040.1); Has 1924 Blast hits to 1907 proteins in 703 species: Archae - 0; Bacteria - 0; Metazoa - 1315; Fungi - 12; Plants - 485; Viruses - 0; Other Eukaryotes - 112 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      17523071..17526126 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_129762.6 → NP_181729.1  Protein with RING/U-box and TRAF-like domain [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_181729.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P93748
      UniProtKB/TrEMBL
      A0A178VZ75, A0A5S9X677
      Conserved Domains (2) summary
      cd16571
      Location:55 → 93
      RING-HC_SIAHs; RING finger, HC subclass, found in Drosophila melanogaster protein Seven-in-Absentia (sina) and its homologs
      pfam03145
      Location:99 → 298
      Sina; Seven in absentia protein family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P93748.1

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