U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    ETC2 Homeodomain-like superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817593, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    ETC2
    Official Full Name
    Homeodomain-like superfamily protein
    Primary source
    TAIR:AT2G30420
    Locus tag
    AT2G30420
    See related
    Araport:AT2G30420
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ENHANCER OF TRY AND CPC 2; T9D9.23; T9D9_23
    Summary
    In a tandem repeat with AT2G30424 and AT2G30432
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See ETC2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    3
    Sequence:
    Chromosome: 2; NC_003071.7 (12960847..12962162, complement)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene ovate family protein 2 Neighboring gene ncRNA Neighboring gene tubulin folding cofactor A (KIESEL) Neighboring gene Homeodomain-like superfamily protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A single amino acid replacement in ETC2 shapes trichome patterning in natural Arabidopsis populations. Hilscher J, et al. Curr Biol, 2009 Nov 3. PMID 19818620, Free PMC Article
    2. Amino acid substitutions in CPC-LIKE MYB reveal residues important for protein stability in Arabidopsis roots. Yamada K, et al. PLoS One, 2018. PMID 30308079, Free PMC Article
    3. ENHANCER of TRY and CPC 2 (ETC2) reveals redundancy in the region-specific control of trichome development of Arabidopsis. Kirik V, et al. Plant Mol Biol, 2004 May. PMID 15604688
    4. Arabidopsis transcription factors: genome-wide comparative analysis among eukaryotes. Riechmann JL, et al. Science, 2000 Dec 15. PMID 11118137
    5. CrY2H-seq: a massively multiplexed assay for deep-coverage interactome mapping. Wanamaker SA, et al. Nat Methods, 2017 Aug. PMID 28650476, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help
    NM_179814.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in negative regulation of trichome patterning IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of DNA-templated transcription TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in root hair cell development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within trichome patterning IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Homeodomain-like superfamily protein
    NP_850145.1
    • ENHANCER OF TRY AND CPC 2 (ETC2); FUNCTIONS IN: DNA binding, sequence-specific DNA binding transcription factor activity; INVOLVED IN: trichome patterning, regulation of transcription; LOCATED IN: mitochondrion; CONTAINS InterPro DOMAIN/s: SANT, DNA-binding (InterPro:IPR001005), Myb, DNA-binding (InterPro:IPR014778), Homeodomain-related (InterPro:IPR012287), Myb transcription factor (InterPro:IPR015495); BEST Arabidopsis thaliana protein match is: Homeodomain-like superfamily protein (TAIR:AT2G30424.1); Has 1991 Blast hits to 1991 proteins in 160 species: Archae - 0; Bacteria - 0; Metazoa - 0; Fungi - 0; Plants - 1974; Viruses - 0; Other Eukaryotes - 17 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      12960847..12962162 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_179814.4 → NP_850145.1  Homeodomain-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850145.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O04349, Q84RD1
      UniProtKB/TrEMBL
      A0A7G2EA76, D6C582
      Conserved Domains (1) summary
      cd00167
      Location:39 → 78
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q84RD1.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools