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    SKL2 shikimate kinase like 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818115, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SKL2
    Official Full Name
    shikimate kinase like 2
    Primary source
    TAIR:AT2G35500
    Locus tag
    AT2G35500
    See related
    Araport:AT2G35500
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    shikimate kinase like 2; shikimate kinase-like 2; T32F12.12; T32F12_12
    Summary
    Encodes a protein with some sequence similarity to shikimate kinases, but a truncated form of this protein (lacking a putative N-terminal chloroplast transit peptide) does not have shikimate kinase activity in vitro.
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    Genomic context

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    See SKL2 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    8
    Sequence:
    Chromosome: 2; NC_003071.7 (14913937..14916668)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene envelope glycoprotein Neighboring gene Plastid-lipid associated protein PAP / fibrillin family protein Neighboring gene uncharacterized protein Neighboring gene Defender against death (DAD family) protein Neighboring gene basic region/leucine zipper transcription factor 16

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The in-vitro synthesized tomato shikimate kinase precursor is enzymatically active and is imported and processed to the mature enzyme by chloroplasts. Schmid J, et al. Plant J, 1992 May. PMID 1338949
    2. Evolutionary diversification of plant shikimate kinase gene duplicates. Fucile G, et al. PLoS Genet, 2008 Dec. PMID 19057671, Free PMC Article
    3. A J-like protein influences fatty acid composition of chloroplast lipids in Arabidopsis. Ajjawi I, et al. PLoS One, 2011. PMID 22028775, Free PMC Article
    4. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article
    5. Evidence for network evolution in an Arabidopsis interactome map. Arabidopsis Interactome Mapping Consortium. Science, 2011 Jul 29. PMID 21798944, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_129102.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    NOT enables shikimate kinase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within aromatic amino acid family biosynthetic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    shikimate kinase like 2
    NP_565805.1
    • shikimate kinase like 2 (SKL2); FUNCTIONS IN: shikimate kinase activity, ATP binding; INVOLVED IN: aromatic amino acid family biosynthetic process; LOCATED IN: chloroplast; EXPRESSED IN: 20 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: CS-like domain (InterPro:IPR007052), Shikimate kinase (InterPro:IPR000623), HSP20-like chaperone (InterPro:IPR008978), CS domain (InterPro:IPR017447); Has 380 Blast hits to 380 proteins in 88 species: Archae - 0; Bacteria - 138; Metazoa - 0; Fungi - 0; Plants - 141; Viruses - 0; Other Eukaryotes - 101 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      14913937..14916668
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_129102.4 → NP_565805.1  shikimate kinase like 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_565805.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O82290, Q945M6
      UniProtKB/TrEMBL
      A0A178VTB9, A0A5S9X487
      Conserved Domains (1) summary
      cd06467
      Location:80 → 169
      p23_NUDC_like; p23_like domain of NUD (nuclear distribution) C and similar proteins. Aspergillus nidulas (An) NUDC is needed for nuclear movement. AnNUDC is localized at the hyphal cortex, and binds NUDF at spindle pole bodies (SPBs) and in the cytoplasm at different ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O82290.2

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