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    NAD(P)-binding Rossmann-fold superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 837034, updated on 18-Sep-2024

    Summary

    Official Full Name
    NAD(P)-binding Rossmann-fold superfamily protein
    Primary source
    TAIR:AT1G05350
    Locus tag
    AT1G05350
    See related
    Araport:AT1G05350
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    YUP8H12.3; YUP8H12_3
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    Genomic context

    Location:
    chromosome: 1
    Exon count:
    14
    Sequence:
    Chromosome: 1; NC_003070.9 (1560678..1564409, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene cysteine-rich TM module stress tolerance protein Neighboring gene vacuole membrane-like protein Neighboring gene Sec14p-like phosphatidylinositol transfer family protein

    General gene information

    NM_100414.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ubiquitin-like modifier activating enzyme activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
     

    General protein information

    Preferred Names
    NAD(P)-binding Rossmann-fold superfamily protein
    NP_172027.2
    • NAD(P)-binding Rossmann-fold superfamily protein; FUNCTIONS IN: binding, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, catalytic activity, cofactor binding; INVOLVED IN: metabolic process; LOCATED IN: cellular_component unknown; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding (InterPro:IPR006140), UBA/THIF-type NAD/FAD binding fold (InterPro:IPR000594), Molybdenum cofactor biosynthesis, MoeB (InterPro:IPR009036), NAD(P)-binding domain (InterPro:IPR016040); BEST Arabidopsis thaliana protein match is: SUMO-activating enzyme 2 (TAIR:AT2G21470.1); Has 12729 Blast hits to 12531 proteins in 2437 species: Archae - 211; Bacteria - 8204; Metazoa - 1010; Fungi - 713; Plants - 367; Viruses - 0; Other Eukaryotes - 2224 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      1560678..1564409 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_100414.4NP_172027.2  NAD(P)-binding Rossmann-fold superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_172027.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O23034
      UniProtKB/TrEMBL
      A0A178WGP0, A0A5S9SQT4
      Conserved Domains (1) summary
      cd00757
      Location:61310
      ThiF_MoeB_HesA_family; ThiF_MoeB_HesA. Family of E1-like enzymes involved in molybdopterin and thiamine biosynthesis family. The common reaction mechanism catalyzed by MoeB and ThiF, like other E1 enzymes, begins with a nucleophilic attack of the C-terminal carboxylate of MoaD ...