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    PATL2 PATELLIN 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 838859, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PATL2
    Official Full Name
    PATELLIN 2
    Primary source
    TAIR:AT1G22530
    Locus tag
    AT1G22530
    See related
    Araport:AT1G22530
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F12K8.13; F12K8_13; PATELLIN 2
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    Genomic context

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    See PATL2 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    4
    Sequence:
    Chromosome: 1; NC_003070.9 (7955445..7958564, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene E3 ubiquitin-protein ligase RNF170-like protein (DUF 1232) Neighboring gene ncRNA Neighboring gene MICOS complex subunit Mic10-like protein (DUF543) Neighboring gene Major facilitator superfamily protein Neighboring gene Major facilitator superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of Phosphoinositide-Binding Protein PATELLIN2 as a Substrate of Arabidopsis MPK4 MAP Kinase during Septum Formation in Cytokinesis. Suzuki T, et al. Plant Cell Physiol, 2016 Aug. PMID 27335345, Free PMC Article
    2. SEC14-GOLD protein PATELLIN2 binds IRON-REGULATED TRANSPORTER1 linking root iron uptake to vitamin E. Hornbergs J, et al. Plant Physiol, 2023 May 2. PMID 36493393, Free PMC Article
    3. PATELLINS are regulators of auxin-mediated PIN1 relocation and plant development in Arabidopsis thaliana. Tejos R, et al. J Cell Sci, 2018 Jan 29. PMID 28687624
    4. The deubiquitinating enzyme AMSH3 is required for intracellular trafficking and vacuole biogenesis in Arabidopsis thaliana. Isono E, et al. Plant Cell, 2010 Jun. PMID 20543027, Free PMC Article
    5. Proteomic analysis of the 26S proteasome reveals its direct interaction with transit peptides of plastid protein precursors for their degradation. Sako K, et al. J Proteome Res, 2014 Jul 3. PMID 24846764

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. SEC14-GOLD protein PATELLIN2 binds IRON-REGULATED TRANSPORTER1 linking root iron uptake to vitamin E.
      Title: SEC14-GOLD protein PATELLIN2 binds IRON-REGULATED TRANSPORTER1 linking root iron uptake to vitamin E.
    2. The PATELLIN2 (PATL2) protein has a SEC14 domain and is a substrate of MPK4 MAP kinase. PATL2 was concentrated at the cell division plane, as is MPK4, and had binding affinity for phosphoinositides.
      Title: Identification of Phosphoinositide-Binding Protein PATELLIN2 as a Substrate of Arabidopsis MPK4 MAP Kinase during Septum Formation in Cytokinesis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001332551.1
    NM_102102.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protease binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to auxin stimulus IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within protein localization involved in auxin polar transport IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus HDA PubMed 
    NOT located_in cytosol RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in nucleus HDA PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plasma membrane HDA PubMed 

    General protein information

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    Preferred Names
    PATELLIN 2
    NP_173669.1
    • PATELLIN 2 (PATL2); FUNCTIONS IN: transporter activity; INVOLVED IN: transport; LOCATED IN: plasma membrane, chloroplast; EXPRESSED IN: 25 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Cellular retinaldehyde-binding/triple function, C-terminal (InterPro:IPR001251), Cellular retinaldehyde-binding/triple function, N-terminal (InterPro:IPR008273), Cellular retinaldehyde binding/alpha-tocopherol transport (InterPro:IPR001071), GOLD (InterPro:IPR009038), Phosphatidylinositol transfer protein-like, N-terminal (InterPro:IPR011074); BEST Arabidopsis thaliana protein match is: PATELLIN 1 (TAIR:AT1G72150.1); Has 61558 Blast hits to 35948 proteins in 2575 species: Archae - 235; Bacteria - 13717; Metazoa - 20974; Fungi - 8097; Plants - 3493; Viruses - 317; Other Eukaryotes - 14725 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      7955445..7958564 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_102102.3 → NP_173669.1  PATELLIN 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_173669.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q56ZI2, Q9SK94
      UniProtKB/TrEMBL
      A0A178WBS6
      Conserved Domains (2) summary
      smart01100
      Location:357 → 389
      CRAL_TRIO_N; CRAL/TRIO, N-terminal domain
      cd00170
      Location:410 → 571
      SEC14; Sec14p-like lipid-binding domain. Found in secretory proteins, such as S. cerevisiae phosphatidylinositol transfer protein (Sec14p), and in lipid regulated proteins such as RhoGAPs, RhoGEFs and neurofibromin (NF1). SEC14 domain of Dbl is known to ...

    2. NM_001332551.1 → NP_001320685.1  PATELLIN 2 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178WBS6, A0A1P8ANK1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q56ZI2.2

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