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    TPX1 thioredoxin-dependent peroxidase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842910, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TPX1
    Official Full Name
    thioredoxin-dependent peroxidase 1
    Primary source
    TAIR:AT1G65980
    Locus tag
    AT1G65980
    See related
    Araport:AT1G65980
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F12P19.14; F12P19_14; PEROXIREDOXIN TPX1; thioredoxin-dependent peroxidase 1
    Summary
    thioredoxin-dependent peroxidase
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    Genomic context

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    See TPX1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    3
    Sequence:
    Chromosome: 1; NC_003070.9 (24559253..24560980, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene glutamate decarboxylase 2 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene thioredoxin-dependent peroxidase 2 Neighboring gene transmembrane protein, putative (DUF247) Neighboring gene type 2 peroxiredoxin-related / thiol specific antioxidant / mal allergen family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Arabidopsis Proteins AtNHR2A and AtNHR2B Are Multi-Functional Proteins Integrating Plant Immunity With Other Biological Processes. Singh R, et al. Front Plant Sci, 2020. PMID 32194606, Free PMC Article
    2. A high content in lipid-modified peripheral proteins and integral receptor kinases features in the arabidopsis plasma membrane proteome. Marmagne A, et al. Mol Cell Proteomics, 2007 Nov. PMID 17644812
    3. A proteomic strategy for global analysis of plant protein complexes. Aryal UK, et al. Plant Cell, 2014 Oct. PMID 25293756, Free PMC Article
    4. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article
    5. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001334230.1
    NM_105270.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables thioredoxin peroxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cellular response to oxidative stress IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 
    located_in nucleus HDA PubMed 
    located_in plasma membrane HDA PubMed 

    General protein information

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    Preferred Names
    thioredoxin-dependent peroxidase 1
    NP_001319329.1
    • thioredoxin-dependent peroxidase 1 (TPX1); FUNCTIONS IN: oxidoreductase activity, antioxidant activity; INVOLVED IN: response to cadmium ion; LOCATED IN: chloroplast, plasma membrane, membrane; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), Thioredoxin-like (InterPro:IPR017936), Thioredoxin-like fold (InterPro:IPR012336), Redoxin (InterPro:IPR013740); BEST Arabidopsis thaliana protein match is: thioredoxin-dependent peroxidase 2 (TAIR:AT1G65970.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_176773.1
    • thioredoxin-dependent peroxidase 1 (TPX1); FUNCTIONS IN: oxidoreductase activity, antioxidant activity; INVOLVED IN: response to cadmium ion; LOCATED IN: chloroplast, plasma membrane, membrane; EXPRESSED IN: 27 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Thioredoxin fold (InterPro:IPR012335), Thioredoxin-like (InterPro:IPR017936), Redoxin (InterPro:IPR013740), Thioredoxin-like fold (InterPro:IPR012336); BEST Arabidopsis thaliana protein match is: thioredoxin-dependent peroxidase 2 (TAIR:AT1G65970.1); Has 3982 Blast hits to 3982 proteins in 881 species: Archae - 11; Bacteria - 1524; Metazoa - 175; Fungi - 308; Plants - 230; Viruses - 0; Other Eukaryotes - 1734 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      24559253..24560980 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_105270.3 → NP_176773.1  thioredoxin-dependent peroxidase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_176773.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9XEX2
      UniProtKB/TrEMBL
      A0A178W6B9, A0A654ELR5
      Conserved Domains (1) summary
      cd03013
      Location:6 → 160
      PRX5_like; Peroxiredoxin (PRX) family, PRX5-like subfamily; members are similar to the human protein, PRX5, a homodimeric TRX peroxidase, widely expressed in tissues and found cellularly in mitochondria, peroxisomes and the cytosol. The cellular location of PRX5 ...

    2. NM_001334230.1 → NP_001319329.1  thioredoxin-dependent peroxidase 1 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4ID64
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9XEX2.1

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