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    KINESIN-12B phragmoplast-associated kinesin-related protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821947, updated on 18-Sep-2024

    Summary

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    Official Symbol
    KINESIN-12B
    Official Full Name
    phragmoplast-associated kinesin-related protein
    Primary source
    TAIR:AT3G23670
    Locus tag
    AT3G23670
    See related
    Araport:AT3G23670
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    PAKRP1L
    Summary
    Microtubule motor kinesin PAKRP1L/Kinesin-12B. Together with PAKRP1/Kinesin-12A, serve as linkers of the plus ends of antiparallel microtubules in the phragmoplast.
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    Genomic context

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    See KINESIN-12B in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    16
    Sequence:
    Chromosome: 3; NC_003074.8 (8519136..8525289)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Sec23/Sec24 protein transport family protein Neighboring gene F-box associated ubiquitination effector family protein Neighboring gene F-box associated ubiquitination effector family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Two Arabidopsis phragmoplast-associated kinesins play a critical role in cytokinesis during male gametogenesis. Lee YR, et al. Plant Cell, 2007 Aug. PMID 17720869, Free PMC Article
    2. Localization of two homologous Arabidopsis kinesin-related proteins in the phragmoplast. Pan R, et al. Planta, 2004 Nov. PMID 15258761
    3. Arabidopsis Fused kinase and the Kinesin-12 subfamily constitute a signalling module required for phragmoplast expansion. Oh SA, et al. Plant J, 2012 Oct. PMID 22709276
    4. Arabidopsis Fused kinase TWO-IN-ONE dominantly inhibits male meiotic cytokinesis. Oh SA, et al. Plant Reprod, 2014 Mar. PMID 24146312
    5. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. TIO and Kinesin-12 constitute a signalling module that is required to support phragmoplast expansion and cell-plate growth in plant cells.
      Title: Arabidopsis Fused kinase and the Kinesin-12 subfamily constitute a signalling module required for phragmoplast expansion.
    2. Kinesin-12 members serve as dynamic linkers of the plus ends of antiparallel microtubules in the phragmoplast.
      Title: Two Arabidopsis phragmoplast-associated kinesins play a critical role in cytokinesis during male gametogenesis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001035673.2
    NM_113271.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables microtubule motor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables plus-end-directed microtubule motor activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within male meiosis cytokinesis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within microgametogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in microtubule-based movement IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within phragmoplast assembly IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in phragmoplast microtubule organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in phragmoplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    phragmoplast-associated kinesin-related protein
    NP_001030750.1
    • KINESIN-12B; FUNCTIONS IN: microtubule motor activity, plus-end-directed microtubule motor activity; INVOLVED IN: phragmoplast assembly, microgametogenesis; LOCATED IN: chloroplast; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Kinesin, motor region, conserved site (InterPro:IPR019821), Kinesin-related protein (InterPro:IPR010544), Kinesin, motor domain (InterPro:IPR001752); BEST Arabidopsis thaliana protein match is: phragmoplast-associated kinesin-related protein 1 (TAIR:AT4G14150.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_189009.2
    • KINESIN-12B; FUNCTIONS IN: microtubule motor activity, plus-end-directed microtubule motor activity; INVOLVED IN: phragmoplast assembly, microgametogenesis; LOCATED IN: chloroplast; EXPRESSED IN: 16 plant structures; EXPRESSED DURING: 9 growth stages; CONTAINS InterPro DOMAIN/s: Kinesin, motor region, conserved site (InterPro:IPR019821), Kinesin-related protein (InterPro:IPR010544), Kinesin, motor domain (InterPro:IPR001752); BEST Arabidopsis thaliana protein match is: phragmoplast-associated kinesin-related protein 1 (TAIR:AT4G14150.1); Has 21997 Blast hits to 17774 proteins in 804 species: Archae - 113; Bacteria - 909; Metazoa - 11671; Fungi - 2303; Plants - 2314; Viruses - 18; Other Eukaryotes - 4669 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      8519136..8525289
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_113271.4 → NP_189009.2  phragmoplast-associated kinesin-related protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_189009.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8L7Y8, Q9LUG0
      UniProtKB/TrEMBL
      A0A178VCW3
      Conserved Domains (3) summary
      PLN03188
      Location:1 → 1313
      PLN03188; kinesin-12 family protein; Provisional
      cl22853
      Location:97 → 439
      Motor_domain; Myosin and Kinesin motor domain
      pfam12711
      Location:911 → 997
      Kinesin-relat_1; Kinesin motor

    2. NM_001035673.2 → NP_001030750.1  phragmoplast-associated kinesin-related protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001030750.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      F4J464
      Conserved Domains (2) summary
      smart00129
      Location:97 → 438
      KISc; Kinesin motor, catalytic domain. ATPase
      cl22853
      Location:97 → 439
      Motor_domain; Myosin and Kinesin motor domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8L7Y8.1

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