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    D-3-phosphoglycerate dehydrogenase [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821482, updated on 18-Sep-2024

    Summary

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    Official Full Name
    D-3-phosphoglycerate dehydrogenase
    Primary source
    TAIR:AT3G19480
    Locus tag
    AT3G19480
    See related
    Araport:AT3G19480
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    3-PGDH; PGDH3; phosphoglycerate dehydrogenase 3
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    Genomic context

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    Location:
    chromosome: 3
    Exon count:
    4
    Sequence:
    Chromosome: 3; NC_003074.8 (6752422..6754785)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Reticulon family protein Neighboring gene F-box and associated interaction domains-containing protein Neighboring gene sodium:hydrogen antiporter 1 Neighboring gene basic helix-loop-helix (bHLH) DNA-binding superfamily protein Neighboring gene complex 1 protein, LYR family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Stromal NADH supplied by PHOSPHOGLYCERATE DEHYDROGENASE3 is crucial for photosynthetic performance. Höhner R, et al. Plant Physiol, 2021 May 27. PMID 33779763, Free PMC Article
    2. Functional characterization of the plastidial 3-phosphoglycerate dehydrogenase family in Arabidopsis. Toujani W, et al. Plant Physiol, 2013 Nov. PMID 24058165, Free PMC Article
    3. Experimental analysis of the Arabidopsis mitochondrial proteome highlights signaling and regulatory components, provides assessment of targeting prediction programs, and indicates plant-specific mitochondrial proteins. Heazlewood JL, et al. Plant Cell, 2004 Jan. PMID 14671022, Free PMC Article
    4. AT_CHLORO, a comprehensive chloroplast proteome database with subplastidial localization and curated information on envelope proteins. Ferro M, et al. Mol Cell Proteomics, 2010 Jun. PMID 20061580, Free PMC Article
    5. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_112835.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables NAD binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables NADH dehydrogenase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphoglycerate dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in L-serine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within photosynthetic acclimation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in chloroplast HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast stroma HDA PubMed 
    located_in chloroplast stroma IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 

    General protein information

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    Preferred Names
    D-3-phosphoglycerate dehydrogenase
    NP_566637.2
    • D-3-phosphoglycerate dehydrogenase; FUNCTIONS IN: in 7 functions; INVOLVED IN: oxidation reduction, L-serine biosynthetic process, metabolic process; LOCATED IN: mitochondrion, chloroplast; EXPRESSED IN: 19 plant structures; EXPRESSED DURING: 10 growth stages; CONTAINS InterPro DOMAIN/s: D-3-phosphoglycerate dehydrogenase (InterPro:IPR006236), D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain (InterPro:IPR006139), D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding (InterPro:IPR006140), D-3-phosphogylcerate Dehydrogenase (InterPro:IPR015508), Amino acid-binding ACT (InterPro:IPR002912), NAD(P)-binding domain (InterPro:IPR016040); BEST Arabidopsis thaliana protein match is: D-3-phosphoglycerate dehydrogenase (TAIR:AT4G34200.1); Has 31099 Blast hits to 31093 proteins in 2807 species: Archae - 469; Bacteria - 19090; Metazoa - 735; Fungi - 1166; Plants - 566; Viruses - 5; Other Eukaryotes - 9068 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      6752422..6754785
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_112835.4 → NP_566637.2  D-3-phosphoglycerate dehydrogenase [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566637.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q94B47, Q9LT69
      UniProtKB/TrEMBL
      A0A5S9XE93, A0A654F8R9, A0A7G2EN38
      Conserved Domains (1) summary
      PRK13581
      Location:47 → 588
      PRK13581; D-3-phosphoglycerate dehydrogenase; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LT69.1

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