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    RAB7B RAB GTPase homolog G3F [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821415, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RAB7B
    Official Full Name
    RAB GTPase homolog G3F
    Primary source
    TAIR:AT3G18820
    Locus tag
    AT3G18820
    See related
    Araport:AT3G18820
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATRAB7B; ATRABG3F; RAB GTPase homolog G3F; RAB71; RABG3F
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    Genomic context

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    See RAB7B in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    6
    Sequence:
    Chromosome: 3; NC_003074.8 (6484068..6486264)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Protein kinase superfamily protein Neighboring gene tRNA-Thr Neighboring gene ncRNA Neighboring gene polyol/monosaccharide transporter 5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Interaction between VPS35 and RABG3f is necessary as a checkpoint to control fusion of late compartments with the vacuole. Rodriguez-Furlan C, et al. Proc Natl Acad Sci U S A, 2019 Oct 15. PMID 31570580, Free PMC Article
    2. Mechanisms governing the endosomal membrane recruitment of the core retromer in Arabidopsis. Zelazny E, et al. J Biol Chem, 2013 Mar 29. PMID 23362252, Free PMC Article
    3. MONENSIN SENSITIVITY1 (MON1)/CALCIUM CAFFEINE ZINC SENSITIVITY1 (CCZ1)-Mediated Rab7 Activation Regulates Tapetal Programmed Cell Death and Pollen Development. Cui Y, et al. Plant Physiol, 2017 Jan. PMID 27799422, Free PMC Article
    4. Activation of the Rab7 GTPase by the MON1-CCZ1 Complex Is Essential for PVC-to-Vacuole Trafficking and Plant Growth in Arabidopsis. Cui Y, et al. Plant Cell, 2014 May. PMID 24824487, Free PMC Article
    5. Distinct sets of tethering complexes, SNARE complexes, and Rab GTPases mediate membrane fusion at the vacuole in Arabidopsis. Takemoto K, et al. Proc Natl Acad Sci U S A, 2018 Mar 6. PMID 29463724, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. MON1/CALCIUM CAFFEINE ZINC SENSITIVITY1 (CCZ1)-mediated Rab7 activation was indispensable for vacuolar trafficking of tapetum degradation-related cysteine proteases.
      Title: MONENSIN SENSITIVITY1 (MON1)/CALCIUM CAFFEINE ZINC SENSITIVITY1 (CCZ1)-Mediated Rab7 Activation Regulates Tapetal Programmed Cell Death and Pollen Development.
    2. Arabidopsis Rab7 homolog RABG3f participates in the recruitment of the core retromer to the endosomal membrane by interacting with VPS35
      Title: Mechanisms governing the endosomal membrane recruitment of the core retromer in Arabidopsis.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    NM_112768.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in intracellular protein transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in late endosome to vacuole transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in vacuole organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus HDA PubMed 
    located_in cytosol HDA PubMed 
    located_in endosome membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in intracellular anatomical structure IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    located_in nucleus HDA PubMed 
    located_in plant-type vacuole membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane HDA PubMed 

    General protein information

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    Preferred Names
    RAB GTPase homolog G3F
    NP_188512.1
    • RAB GTPase homolog G3F (RAB7B); FUNCTIONS IN: GTP binding; INVOLVED IN: protein transport, small GTPase mediated signal transduction; LOCATED IN: plasma membrane, nucleus; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Ras GTPase (InterPro:IPR001806), Small GTP-binding protein (InterPro:IPR005225), Small GTPase (InterPro:IPR020851), Ras (InterPro:IPR013753), Ras small GTPase, Rab type (InterPro:IPR003579); BEST Arabidopsis thaliana protein match is: RAB GTPase homolog G3E (TAIR:AT1G49300.2); Has 26432 Blast hits to 26399 proteins in 759 species: Archae - 38; Bacteria - 171; Metazoa - 13566; Fungi - 4011; Plants - 2887; Viruses - 20; Other Eukaryotes - 5739 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      6484068..6486264
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_112768.3 → NP_188512.1  RAB GTPase homolog G3F [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_188512.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LGH5, Q9LS94
      UniProtKB/TrEMBL
      A0A178VI56, A0A178W3Y1, A0A5S9XE12
      Conserved Domains (1) summary
      cd01862
      Location:9 → 182
      Rab7; Rab GTPase family 7 (Rab7)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9LS94.1

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