PA200 proteasome activating protein 200 [Arabidopsis thaliana (thale cress)] - Gene

Summary

Go to the top of the page Help

Official Symbol: PA200
Official Full Name: proteasome activating protein 200
Primary source: TAIR:AT3G13330
Locus tag: AT3G13330
See related: Araport:AT3G13330
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Arabidopsis thaliana (ecotype: Columbia)
Lineage: Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
Also known as: proteasome activating protein 200
Summary: Encodes a protein that interacts with the 26S proteasome. Mutants are phenotypically indistinguishable from wild type plants under a variety of growth conditions. Protein levels increase upon exposure of seedlings to MG132, a specific, potent, reversible, and cell-permeable proteasome inhibitor.
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help

See PA200 in Genome Data Viewer

Location:: chromosome: 3

Exon count:: 35

Sequence:: Chromosome: 3; NC_003074.8 (4319490..4330218, complement)

Chromosome 3 - NC_003074.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_003074.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Homology

Orthologs from OrthoDB

NM_001338043.1

Supported by ESTs:

Gene Ontology Provided by TAIR

Function	Evidence Code	Pubs
enables lysine-acetylated histone binding	IEA Inferred from Electronic Annotation more info
enables peptidase activator activity	IEA Inferred from Electronic Annotation more info
enables proteasome binding	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nucleus	ISM Inferred from Sequence Model more info

General protein information

Go to the top of the page Help

Preferred Names: proteasome activating protein 200

NP_001319538.1

proteasome activating protein 200 (PA200); FUNCTIONS IN: binding; LOCATED IN: cellular_component unknown; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Protein of unknown function DUF3437 (InterPro:IPR021843), Armadillo-type fold (InterPro:IPR016024); Has 512 Blast hits to 355 proteins in 156 species: Archae - 0; Bacteria - 0; Metazoa - 127; Fungi - 262; Plants - 57; Viruses - 0; Other Eukaryotes - 66 (source: NCBI BLink).

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003074.8 Reference assembly

Range

4319490..4330218 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001338043.1 → NP_001319538.1 proteasome activating protein 200 [Arabidopsis thaliana]

Status: REVIEWED

UniProtKB/Swiss-Prot

F4JC97, Q8RXU1, Q9LTT5

UniProtKB/TrEMBL

A0A178VC52, A0A5S9XBQ3, A0A7G2EPN6

Conserved Domains (3) summary

sd00044
Location:1582 → 1607

HEAT; HEAT repeat [structural motif]

pfam11919
Location:1728 → 1810

DUF3437; Domain of unknown function (DUF3437)

pfam16507
Location:309 → 807

BLM10_mid; Proteasome-substrate-size regulator, mid region