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    SCAR4 SCAR family protein 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 831687, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SCAR4
    Official Full Name
    SCAR family protein 4
    Primary source
    TAIR:AT5G01730
    Locus tag
    AT5G01730
    See related
    Araport:AT5G01730
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATSCAR4; F7A7.250; F7A7_250; SCAR family protein 4; WAVE3
    Summary
    Encodes a member of the SCAR family.These proteins are part of a complex (WAVE) complex.The SCAR subunit activates the ARP2/3 complex which in turn act as a nucleator for actin filaments.
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    Genomic context

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    See SCAR4 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    9
    Sequence:
    Chromosome: 5; NC_003076.8 (272832..277886, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene RNI-like superfamily protein Neighboring gene ncRNA Neighboring gene miscRNA Neighboring gene ncRNA Neighboring gene Nuclear transport factor 2 (NTF2) family protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis SCARs function interchangeably to meet actin-related protein 2/3 activation thresholds during morphogenesis. Zhang C, et al. Plant Cell, 2008 Apr. PMID 18424615, Free PMC Article
    2. The role of Arabidopsis SCAR genes in ARP2-ARP3-dependent cell morphogenesis. Uhrig JF, et al. Development, 2007 Mar. PMID 17267444
    3. Tocopherol cyclase (VTE1) localization and vitamin E accumulation in chloroplast plastoglobule lipoprotein particles. Vidi PA, et al. J Biol Chem, 2006 Apr 21. PMID 16414959
    4. Sorting signals, N-terminal modifications and abundance of the chloroplast proteome. Zybailov B, et al. PLoS One, 2008 Apr 23. PMID 18431481, Free PMC Article
    5. Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana. Tabata S, et al. Nature, 2000 Dec 14. PMID 11130714

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001342607.1
    NM_001342608.1
    NM_001342609.1
    NM_001342610.1
    NM_001342611.1
    NM_001342612.1
    NM_001342613.1
    NM_001342614.1
    NM_001342615.1
    NM_001342616.1
    NM_120251.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within positive regulation of actin nucleation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of SCAR complex TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in chloroplast HDA PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in plastoglobule HDA PubMed 

    General protein information

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    Preferred Names
    SCAR family protein 4
    NP_001318456.1
    • SCAR family protein 4 (SCAR4); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: positive regulation of actin nucleation; LOCATED IN: SCAR complex, chloroplast, plastoglobule; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 12 growth stages; BEST Arabidopsis thaliana protein match is: SCAR homolog 2 (TAIR:AT2G38440.1); Has 1330 Blast hits to 874 proteins in 188 species: Archae - 2; Bacteria - 349; Metazoa - 454; Fungi - 169; Plants - 213; Viruses - 0; Other Eukaryotes - 143 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      272832..277886 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001342607.1 → NP_001318456.1  SCAR family protein 4 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q5XPJ6, Q9LCZ7
      UniProtKB/TrEMBL
      A0A5S9Y0Y0, A0A654FXX5

    2. NM_001342610.1 → NP_001330637.1  SCAR family protein 4 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BBH5

    3. NM_120251.4 → NP_195793.3  SCAR family protein 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_195793.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q5XPJ6, Q9LCZ7
      UniProtKB/TrEMBL
      A0A5S9Y0Y0, A0A654FXX5

    4. NM_001342611.1 → NP_001330636.1  SCAR family protein 4 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BBH5

    5. NM_001342612.1 → NP_001330633.1  SCAR family protein 4 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BBH5

    6. NM_001342613.1 → NP_001330635.1  SCAR family protein 4 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BBE5

    7. NM_001342614.1 → NP_001330634.1  SCAR family protein 4 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BBE9

    8. NM_001342615.1 → NP_001330639.1  SCAR family protein 4 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BBE9

    9. NM_001342616.1 → NP_001330638.1  SCAR family protein 4 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BBE6

    10. NM_001342609.1 → NP_001330631.1  SCAR family protein 4 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178UA95, A0A1P8BBE7, A0A384KVX1

    11. NM_001342608.1 → NP_001330632.1  SCAR family protein 4 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BBE8
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5XPJ6.1

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