U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    TOPP8 Calcineurin-like metallo-phosphoesterase superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 832846, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    TOPP8
    Official Full Name
    Calcineurin-like metallo-phosphoesterase superfamily protein
    Primary source
    TAIR:AT5G27840
    Locus tag
    AT5G27840
    See related
    Araport:AT5G27840
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    T1G16.170; T1G16_170
    Summary
    encodes a serine/threonine protein phosphatase expressed in expressed in roots, rosettes and flowers.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See TOPP8 in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    5
    Sequence:
    Chromosome: 5; NC_003076.8 (9862923..9865172, complement)

    Chromosome 5 - NC_003076.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Ribosomal L18p/L5e family protein Neighboring gene folate receptor family protein Neighboring gene pseudo Neighboring gene Ribosomal protein L18e/L15 superfamily protein Neighboring gene uncharacterized protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003076.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The Protein Phosphatases ATUNIS1 and ATUNIS2 Regulate Cell Wall Integrity in Tip-Growing Cells. Franck CM, et al. Plant Cell, 2018 Aug. PMID 29991535, Free PMC Article
    2. Molecular cloning and chromosomal mapping of type one serine/threonine protein phosphatases in Arabidopsis thaliana. Lin Q, et al. Plant Mol Biol, 1998 Jun. PMID 9617814
    3. Identification and characterization of AtI-2, an Arabidopsis homologue of an ancient protein phosphatase 1 (PP1) regulatory subunit. Templeton GW, et al. Biochem J, 2011 Apr 1. PMID 21222654
    4. Identification and functional characterization of inhibitor-3, a regulatory subunit of protein phosphatase 1 in plants. Takemiya A, et al. Plant Physiol, 2009 May. PMID 19329567, Free PMC Article
    5. Genome-wide biochemical analysis of Arabidopsis protein phosphatase using a wheat cell-free system. Takahashi H, et al. FEBS Lett, 2012 Sep 21. PMID 22968126

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    NM_001344042.1
    NM_001344043.1
    NM_122666.4
    NM_180754.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables myosin phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine phosphatase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein serine/threonine phosphatase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables protein serine/threonine phosphatase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within pollen tube growth IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within protein dephosphorylation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    acts_upstream_of_or_within root hair cell tip growth IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    Calcineurin-like metallo-phosphoesterase superfamily protein
    NP_568501.3
    • TOPP8; CONTAINS InterPro DOMAIN/s: Metallophosphoesterase (InterPro:IPR004843), Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase (InterPro:IPR006186); BEST Arabidopsis thaliana protein match is: Calcineurin-like metallo-phosphoesterase superfamily protein (TAIR:AT3G05580.1); Has 7274 Blast hits to 7088 proteins in 679 species: Archae - 78; Bacteria - 658; Metazoa - 2391; Fungi - 1410; Plants - 989; Viruses - 10; Other Eukaryotes - 1738 (source: NCBI BLink).
    NP_851085.1
    • TOPP8; CONTAINS InterPro DOMAIN/s: Metallophosphoesterase (InterPro:IPR004843), Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase (InterPro:IPR006186); BEST Arabidopsis thaliana protein match is: Calcineurin-like metallo-phosphoesterase superfamily protein (TAIR:AT3G05580.1); Has 7305 Blast hits to 7120 proteins in 684 species: Archae - 78; Bacteria - 668; Metazoa - 2406; Fungi - 1414; Plants - 989; Viruses - 10; Other Eukaryotes - 1740 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003076.8 Reference assembly

      Range
      9862923..9865172 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_180754.4 → NP_851085.1  Calcineurin-like metallo-phosphoesterase superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_851085.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A5S9Y7Y8, A0A654F5S2
      Conserved Domains (1) summary
      cd07414
      Location:13 → 300
      MPP_PP1_PPKL; PP1, PPKL (PP1 and kelch-like) enzymes, and related proteins, metallophosphatase domain

    2. NM_001344042.1 → NP_001330890.1  Calcineurin-like metallo-phosphoesterase superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O82734, Q8LAG7, Q94B49
      UniProtKB/TrEMBL
      A0A654F5S2

    3. NM_001344043.1 → NP_001330891.1  Calcineurin-like metallo-phosphoesterase superfamily protein [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8BC75, A0A654F5S2

    4. NM_122666.4 → NP_568501.3  Calcineurin-like metallo-phosphoesterase superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_568501.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O82734, Q8LAG7, Q94B49
      UniProtKB/TrEMBL
      A0A654F5S2
      Conserved Domains (2) summary
      PTZ00480
      Location:14 → 301
      PTZ00480; serine/threonine-protein phosphatase; Provisional
      cd07414
      Location:13 → 300
      MPP_PP1_PPKL; PP1, PPKL (PP1 and kelch-like) enzymes, and related proteins, metallophosphatase domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O82734.3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.