Col23a1 collagen, type XXIII, alpha 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Col23a1provided by MGI
Official Full Name: collagen, type XXIII, alpha 1provided by MGI
Primary source: MGI:MGI:2653243
See related: Ensembl:ENSMUSG00000063564 AllianceGenome:MGI:2653243
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 2810458L13Rik
Summary: Predicted to enable heparin binding activity and identical protein binding activity. Predicted to be an extracellular matrix structural constituent conferring tensile strength. Predicted to be involved in extracellular matrix organization. Located in collagen-containing extracellular matrix. Is expressed in several structures, including bone; genitourinary system; gut; skin; and somite. Orthologous to human COL23A1 (collagen type XXIII alpha 1 chain). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Broad expression in limb E14.5 (RPKM 8.2), lung adult (RPKM 8.0) and 21 other tissues See more
Orthologs: human all
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Genomic context

Location:: 11 B1.3; 11 31.03 cM

Exon count:: 31

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	11	NC_000077.7 (51180508..51474752)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	11	NC_000077.6 (51289679..51583925)

Chromosome 11 - NC_000077.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

analysis of collagen XXIII mRNA and protein
Title: Expression of type XXIII collagen mRNA and protein.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

RH127063 (e-PCR)
- UniSTS:208674

D11Mit314 (e-PCR), detects polymorphism
- UniSTS:126526

293E15-T7 (e-PCR), detects polymorphism
- UniSTS:140924

RH144145 (e-PCR)
- UniSTS:233391

D11Jcs12 (e-PCR), detects polymorphism
- UniSTS:141754

AI429655 (e-PCR)
- UniSTS:180196

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables extracellular matrix structural constituent conferring tensile strength	IBA Inferred from Biological aspect of Ancestor more info
enables extracellular matrix structural constituent conferring tensile strength	RCA inferred from Reviewed Computational Analysis more info	PubMed
enables heparin binding	IEA Inferred from Electronic Annotation more info
enables heparin binding	ISO Inferred from Sequence Orthology more info
enables identical protein binding	IEA Inferred from Electronic Annotation more info
enables identical protein binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in extracellular matrix organization	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in cell surface	IEA Inferred from Electronic Annotation more info
located_in cell surface	ISO Inferred from Sequence Orthology more info
part_of collagen trimer	IEA Inferred from Electronic Annotation more info
located_in collagen-containing extracellular matrix	HDA more info	PubMed
is_active_in collagen-containing extracellular matrix	IBA Inferred from Biological aspect of Ancestor more info
located_in extracellular region	TAS Traceable Author Statement more info
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info
located_in extracellular space	IEA Inferred from Electronic Annotation more info
located_in extracellular space	ISO Inferred from Sequence Orthology more info
located_in plasma membrane	TAS Traceable Author Statement more info

General protein information

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Preferred Names: collagen alpha-1(XXIII) chain

Names: procollagen, type XXIII, alpha 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_153393.2 → NP_700442.2 collagen alpha-1(XXIII) chain

See identical proteins and their annotated locations for NP_700442.2

Status: PROVISIONAL

Source sequence(s)

AL645907, AL662843

Consensus CDS

CCDS24652.1

UniProtKB/Swiss-Prot

Q5SUQ0, Q8K4G2

Related

ENSMUSP00000099826.3, ENSMUST00000102765.9

Conserved Domains (1) summary

pfam01391
Location:455 → 512

Collagen; Collagen triple helix repeat (20 copies)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000077.7 Reference GRCm39 C57BL/6J

Range

51180508..51474752

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_011248983.4 → XP_011247285.1 collagen alpha-1(XXIII) chain isoform X2

Conserved Domains (1) summary

pfam01391
Location:124 → 168

Collagen; Collagen triple helix repeat (20 copies)
XM_036156655.1 → XP_036012548.1 collagen alpha-1(XXIII) chain isoform X1

Conserved Domains (1) summary

pfam01391
Location:449 → 503

Collagen; Collagen triple helix repeat (20 copies)