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    ZSCAN5A zinc finger and SCAN domain containing 5A [ Homo sapiens (human) ]

    Gene ID: 79149, updated on 10-Dec-2024

    Summary

    Official Symbol
    ZSCAN5Aprovided by HGNC
    Official Full Name
    zinc finger and SCAN domain containing 5Aprovided by HGNC
    Primary source
    HGNC:HGNC:23710
    See related
    Ensembl:ENSG00000131848 MIM:620916; AllianceGenome:HGNC:23710
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    ZNF495; ZSCAN5
    Summary
    Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in testis (RPKM 6.0), kidney (RPKM 0.7) and 21 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See ZSCAN5A in Genome Data Viewer
    Location:
    19q13.43
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (56221303..56368278, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (59320082..59462670, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (56732672..56879647, complement)

    Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene Neanderthal introgressed variant-containing enhancer experimental_51953 Neighboring gene zinc finger and SCAN domain containing 5C Neighboring gene ribosomal protein L13 pseudogene 13 Neighboring gene uncharacterized LOC124904774 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr19:56747404-56748603 Neighboring gene zinc finger and SCAN domain containing 5D pseudogene Neighboring gene uncharacterized LOC124904775 Neighboring gene uncharacterized LOC124900420 Neighboring gene epididymal protein 13 Neighboring gene uncharacterized LOC105372468 Neighboring gene ZSCAN5A antisense RNA 1 Neighboring gene glycerol-3-phosphate dehydrogenase 2 (mitochondrial) pseudogene Neighboring gene vomeronasal 2 receptor 17, pseudogene Neighboring gene NADH:ubiquinone oxidoreductase complex assembly factor 1 pseudogene Neighboring gene vomeronasal 2 receptor 18 pseudogene Neighboring gene Sharpr-MPRA regulatory region 13801 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 15118 Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr19:56888366-56889565 Neighboring gene zinc finger protein 542, pseudogene Neighboring gene BRD4-independent group 4 enhancer GRCh37_chr19:56895030-56896229 Neighboring gene SLC25A36 pseudogene 1 Neighboring gene zinc finger protein 582 Neighboring gene ZNF582 divergent transcript

    Genomic regions, transcripts, and products

    Expression

    • Project title: Tissue-specific circular RNA induction during human fetal development
    • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
    • BioProject: PRJNA270632
    • Publication: PMID 26076956
    • Analysis date: Mon Apr 2 22:54:59 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    zinc finger and SCAN domain-containing protein 5A
    Names
    zinc finger and SCAN domain containing 5
    zinc finger protein 495

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001322061.4NP_001308990.2  zinc finger and SCAN domain-containing protein 5A isoform c

      Status: VALIDATED

      Source sequence(s)
      AC006116, AC011506
      Consensus CDS
      CCDS82403.1
      UniProtKB/TrEMBL
      A0A0C4DGQ1
      Conserved Domains (4) summary
      cd07936
      Location:40124
      SCAN; SCAN oligomerization domain
      COG5048
      Location:338491
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:413433
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:453478
      zf-H2C2_2; Zinc-finger double domain
    2. NM_001322062.2NP_001308991.2  zinc finger and SCAN domain-containing protein 5A isoform c

      Status: VALIDATED

      Source sequence(s)
      AC011506
      Consensus CDS
      CCDS82403.1
      UniProtKB/TrEMBL
      A0A0C4DGQ1
      Related
      ENSP00000467238.1, ENST00000592355.5
      Conserved Domains (4) summary
      cd07936
      Location:40124
      SCAN; SCAN oligomerization domain
      COG5048
      Location:338491
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:413433
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:453478
      zf-H2C2_2; Zinc-finger double domain
    3. NM_001322064.3NP_001308993.1  zinc finger and SCAN domain-containing protein 5A isoform b

      Status: VALIDATED

      Source sequence(s)
      AC006116, AC011506
      Consensus CDS
      CCDS12941.1
      UniProtKB/Swiss-Prot
      B4DX98, Q49A73, Q53F04, Q8N7B3, Q9BUG6
      Related
      ENSP00000507065.1, ENST00000683990.1
      Conserved Domains (5) summary
      TIGR00934
      Location:117328
      2a38euk; potassium uptake protein, Trk family
      cd07936
      Location:40124
      SCAN; SCAN oligomerization domain
      COG5048
      Location:339492
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:414434
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:454479
      zf-H2C2_2; Zinc-finger double domain
    4. NM_001322065.3NP_001308994.1  zinc finger and SCAN domain-containing protein 5A isoform b

      Status: VALIDATED

      Source sequence(s)
      AC006116, AC011506
      Consensus CDS
      CCDS12941.1
      UniProtKB/Swiss-Prot
      B4DX98, Q49A73, Q53F04, Q8N7B3, Q9BUG6
      Conserved Domains (5) summary
      TIGR00934
      Location:117328
      2a38euk; potassium uptake protein, Trk family
      cd07936
      Location:40124
      SCAN; SCAN oligomerization domain
      COG5048
      Location:339492
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:414434
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:454479
      zf-H2C2_2; Zinc-finger double domain
    5. NM_001322066.2NP_001308995.1  zinc finger and SCAN domain-containing protein 5A isoform b

      Status: VALIDATED

      Source sequence(s)
      AC006116, AC011506
      Consensus CDS
      CCDS12941.1
      UniProtKB/Swiss-Prot
      B4DX98, Q49A73, Q53F04, Q8N7B3, Q9BUG6
      Conserved Domains (5) summary
      TIGR00934
      Location:117328
      2a38euk; potassium uptake protein, Trk family
      cd07936
      Location:40124
      SCAN; SCAN oligomerization domain
      COG5048
      Location:339492
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:414434
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:454479
      zf-H2C2_2; Zinc-finger double domain
    6. NM_001322067.2NP_001308996.1  zinc finger and SCAN domain-containing protein 5A isoform b

      Status: VALIDATED

      Source sequence(s)
      AC006116, AC011506
      Consensus CDS
      CCDS12941.1
      UniProtKB/Swiss-Prot
      B4DX98, Q49A73, Q53F04, Q8N7B3, Q9BUG6
      Conserved Domains (5) summary
      TIGR00934
      Location:117328
      2a38euk; potassium uptake protein, Trk family
      cd07936
      Location:40124
      SCAN; SCAN oligomerization domain
      COG5048
      Location:339492
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:414434
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:454479
      zf-H2C2_2; Zinc-finger double domain
    7. NM_001322068.2NP_001308997.1  zinc finger and SCAN domain-containing protein 5A isoform b

      Status: VALIDATED

      Source sequence(s)
      AC006116, AC011506
      Consensus CDS
      CCDS12941.1
      UniProtKB/Swiss-Prot
      B4DX98, Q49A73, Q53F04, Q8N7B3, Q9BUG6
      Conserved Domains (5) summary
      TIGR00934
      Location:117328
      2a38euk; potassium uptake protein, Trk family
      cd07936
      Location:40124
      SCAN; SCAN oligomerization domain
      COG5048
      Location:339492
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:414434
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:454479
      zf-H2C2_2; Zinc-finger double domain
    8. NM_001322070.2NP_001308999.1  zinc finger and SCAN domain-containing protein 5A isoform b

      Status: VALIDATED

      Source sequence(s)
      AC006116, AC011506
      Consensus CDS
      CCDS12941.1
      UniProtKB/Swiss-Prot
      B4DX98, Q49A73, Q53F04, Q8N7B3, Q9BUG6
      Conserved Domains (5) summary
      TIGR00934
      Location:117328
      2a38euk; potassium uptake protein, Trk family
      cd07936
      Location:40124
      SCAN; SCAN oligomerization domain
      COG5048
      Location:339492
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:414434
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:454479
      zf-H2C2_2; Zinc-finger double domain
    9. NM_001322072.3NP_001309001.1  zinc finger and SCAN domain-containing protein 5A isoform b

      Status: VALIDATED

      Source sequence(s)
      AC006116, AC011506
      Consensus CDS
      CCDS12941.1
      UniProtKB/Swiss-Prot
      B4DX98, Q49A73, Q53F04, Q8N7B3, Q9BUG6
      Related
      ENSP00000467631.1, ENST00000587340.5
      Conserved Domains (5) summary
      TIGR00934
      Location:117328
      2a38euk; potassium uptake protein, Trk family
      cd07936
      Location:40124
      SCAN; SCAN oligomerization domain
      COG5048
      Location:339492
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:414434
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:454479
      zf-H2C2_2; Zinc-finger double domain
    10. NM_001322073.2NP_001309002.1  zinc finger and SCAN domain-containing protein 5A isoform c

      Status: VALIDATED

      Source sequence(s)
      AC006116, AC011506
      Consensus CDS
      CCDS82403.1
      UniProtKB/TrEMBL
      A0A0C4DGQ1
      Conserved Domains (4) summary
      cd07936
      Location:40124
      SCAN; SCAN oligomerization domain
      COG5048
      Location:338491
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:413433
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:453478
      zf-H2C2_2; Zinc-finger double domain
    11. NM_001322074.2NP_001309003.1  zinc finger and SCAN domain-containing protein 5A isoform c

      Status: VALIDATED

      Source sequence(s)
      AC006116, AC011506
      Consensus CDS
      CCDS82403.1
      UniProtKB/TrEMBL
      A0A0C4DGQ1
      Conserved Domains (4) summary
      cd07936
      Location:40124
      SCAN; SCAN oligomerization domain
      COG5048
      Location:338491
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:413433
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:453478
      zf-H2C2_2; Zinc-finger double domain
    12. NM_001322075.2NP_001309004.1  zinc finger and SCAN domain-containing protein 5A isoform c

      Status: VALIDATED

      Source sequence(s)
      AC006116, AC011506
      Consensus CDS
      CCDS82403.1
      UniProtKB/TrEMBL
      A0A0C4DGQ1
      Conserved Domains (4) summary
      cd07936
      Location:40124
      SCAN; SCAN oligomerization domain
      COG5048
      Location:338491
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:413433
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:453478
      zf-H2C2_2; Zinc-finger double domain
    13. NM_001322076.2NP_001309005.1  zinc finger and SCAN domain-containing protein 5A isoform c

      Status: VALIDATED

      Source sequence(s)
      AC006116, AC011506
      Consensus CDS
      CCDS82403.1
      UniProtKB/TrEMBL
      A0A0C4DGQ1
      Conserved Domains (4) summary
      cd07936
      Location:40124
      SCAN; SCAN oligomerization domain
      COG5048
      Location:338491
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:413433
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:453478
      zf-H2C2_2; Zinc-finger double domain
    14. NM_001322077.3NP_001309006.1  zinc finger and SCAN domain-containing protein 5A isoform d

      Status: VALIDATED

      Source sequence(s)
      AC006116, AC011506
      UniProtKB/Swiss-Prot
      Q9BUG6
      Related
      ENSP00000466445.1, ENST00000587492.5
      Conserved Domains (3) summary
      COG5048
      Location:222375
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:297317
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:337362
      zf-H2C2_2; Zinc-finger double domain
    15. NM_001322078.3NP_001309007.1  zinc finger and SCAN domain-containing protein 5A isoform e

      Status: VALIDATED

      Source sequence(s)
      AC006116, AC011506
      UniProtKB/Swiss-Prot
      Q9BUG6
      Conserved Domains (3) summary
      COG5048
      Location:209362
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:284304
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:324349
      zf-H2C2_2; Zinc-finger double domain
    16. NM_001387853.1NP_001374782.1  zinc finger and SCAN domain-containing protein 5A isoform b

      Status: VALIDATED

      Source sequence(s)
      AC006116, AC011506
      Consensus CDS
      CCDS12941.1
      UniProtKB/Swiss-Prot
      B4DX98, Q49A73, Q53F04, Q8N7B3, Q9BUG6
      Conserved Domains (5) summary
      TIGR00934
      Location:117328
      2a38euk; potassium uptake protein, Trk family
      cd07936
      Location:40124
      SCAN; SCAN oligomerization domain
      COG5048
      Location:339492
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:414434
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:454479
      zf-H2C2_2; Zinc-finger double domain
    17. NM_001387854.1NP_001374783.1  zinc finger and SCAN domain-containing protein 5A isoform c

      Status: VALIDATED

      Source sequence(s)
      AC006116, AC011506
      Consensus CDS
      CCDS82403.1
      UniProtKB/TrEMBL
      A0A0C4DGQ1
      Conserved Domains (4) summary
      cd07936
      Location:40124
      SCAN; SCAN oligomerization domain
      COG5048
      Location:338491
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:413433
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:453478
      zf-H2C2_2; Zinc-finger double domain
    18. NM_001387855.1NP_001374784.1  zinc finger and SCAN domain-containing protein 5A isoform c

      Status: VALIDATED

      Source sequence(s)
      AC006116, AC011506
      Consensus CDS
      CCDS82403.1
      UniProtKB/TrEMBL
      A0A0C4DGQ1
      Conserved Domains (4) summary
      cd07936
      Location:40124
      SCAN; SCAN oligomerization domain
      COG5048
      Location:338491
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:413433
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:453478
      zf-H2C2_2; Zinc-finger double domain
    19. NM_001387856.1NP_001374785.1  zinc finger and SCAN domain-containing protein 5A isoform c

      Status: VALIDATED

      Source sequence(s)
      AC006116, AC011506
      Consensus CDS
      CCDS82403.1
      UniProtKB/TrEMBL
      A0A0C4DGQ1
      Conserved Domains (4) summary
      cd07936
      Location:40124
      SCAN; SCAN oligomerization domain
      COG5048
      Location:338491
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:413433
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:453478
      zf-H2C2_2; Zinc-finger double domain
    20. NM_001387857.1NP_001374786.1  zinc finger and SCAN domain-containing protein 5A isoform b

      Status: VALIDATED

      Source sequence(s)
      AC006116, AC011506
      Consensus CDS
      CCDS12941.1
      UniProtKB/Swiss-Prot
      B4DX98, Q49A73, Q53F04, Q8N7B3, Q9BUG6
      Conserved Domains (5) summary
      TIGR00934
      Location:117328
      2a38euk; potassium uptake protein, Trk family
      cd07936
      Location:40124
      SCAN; SCAN oligomerization domain
      COG5048
      Location:339492
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:414434
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:454479
      zf-H2C2_2; Zinc-finger double domain
    21. NM_001387858.1NP_001374787.1  zinc finger and SCAN domain-containing protein 5A isoform c

      Status: VALIDATED

      Source sequence(s)
      AC006116, AC011506
      Consensus CDS
      CCDS82403.1
      UniProtKB/TrEMBL
      A0A0C4DGQ1
      Conserved Domains (4) summary
      cd07936
      Location:40124
      SCAN; SCAN oligomerization domain
      COG5048
      Location:338491
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:413433
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:453478
      zf-H2C2_2; Zinc-finger double domain
    22. NM_001387859.1NP_001374788.1  zinc finger and SCAN domain-containing protein 5A isoform b

      Status: VALIDATED

      Source sequence(s)
      AC006116, AC011506
      Consensus CDS
      CCDS12941.1
      UniProtKB/Swiss-Prot
      B4DX98, Q49A73, Q53F04, Q8N7B3, Q9BUG6
      Conserved Domains (5) summary
      TIGR00934
      Location:117328
      2a38euk; potassium uptake protein, Trk family
      cd07936
      Location:40124
      SCAN; SCAN oligomerization domain
      COG5048
      Location:339492
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:414434
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:454479
      zf-H2C2_2; Zinc-finger double domain
    23. NM_024303.4NP_077279.1  zinc finger and SCAN domain-containing protein 5A isoform b

      See identical proteins and their annotated locations for NP_077279.1

      Status: VALIDATED

      Source sequence(s)
      AC011506
      Consensus CDS
      CCDS12941.1
      UniProtKB/Swiss-Prot
      B4DX98, Q49A73, Q53F04, Q8N7B3, Q9BUG6
      Related
      ENSP00000375593.1, ENST00000391713.5
      Conserved Domains (5) summary
      TIGR00934
      Location:117328
      2a38euk; potassium uptake protein, Trk family
      cd07936
      Location:40124
      SCAN; SCAN oligomerization domain
      COG5048
      Location:339492
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:414434
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:454479
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

      Range
      56221303..56368278 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060943.1 Alternate T2T-CHM13v2.0

      Range
      59320082..59462670 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)