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    Lrrc10b leucine rich repeat containing 10B [ Mus musculus (house mouse) ]

    Gene ID: 278795, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Lrrc10bprovided by MGI
    Official Full Name
    leucine rich repeat containing 10Bprovided by MGI
    Primary source
    MGI:MGI:2685551
    See related
    Ensembl:ENSMUSG00000090291 AllianceGenome:MGI:2685551
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm705; SerdinR
    Summary
    Predicted to be involved in intracellular signal transduction. Is expressed in several structures, including heart; liver; lung; metanephros; and spleen. Orthologous to human LRRC10B (leucine rich repeat containing 10B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human all
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    Genomic context

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    See Lrrc10b in Genome Data Viewer
    Location:
    19 A; 19 6.6 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (10432735..10434811, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (10455371..10457447, complement)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 30263 Neighboring gene synaptotagmin VII Neighboring gene stabilizer of axonemal microtubules 4 Neighboring gene succinate dehydrogenase complex assembly factor 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    leucine-rich repeat-containing protein 10B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001111140.2 → NP_001104610.1  leucine-rich repeat-containing protein 10B

      See identical proteins and their annotated locations for NP_001104610.1

      Status: VALIDATED

      Source sequence(s)
      AC124169
      Consensus CDS
      CCDS50389.1
      UniProtKB/TrEMBL
      G3XA50
      Related
      ENSMUSP00000132865.3, ENSMUST00000171400.4
      Conserved Domains (3) summary
      sd00033
      Location:24 → 45
      LRR_RI; leucine-rich repeat [structural motif]
      pfam12799
      Location:90 → 129
      LRR_4; Leucine Rich repeats (2 copies)
      pfam13855
      Location:90 → 148
      LRR_8; Leucine rich repeat

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      10432735..10434811 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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