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    Tcf24 transcription factor 24 [ Mus musculus (house mouse) ]

    Gene ID: 100039596, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Tcf24provided by MGI
    Official Full Name
    transcription factor 24provided by MGI
    Primary source
    MGI:MGI:3780500
    See related
    Ensembl:ENSMUSG00000099032 AllianceGenome:MGI:3780500
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm2330; Gm10567
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in developmental process and regulation of transcription by RNA polymerase II. Orthologous to human TCF24 (transcription factor 24). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in adrenal adult (RPKM 7.3), placenta adult (RPKM 3.4) and 9 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Tcf24 in Genome Data Viewer
    Location:
    1 A2; 1 2.24 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (10030388..10038207, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (9960163..9967981, complement)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene minichromosome maintenance domain containing 2 Neighboring gene STARR-positive B cell enhancer ABC_E4304 Neighboring gene small nucleolar RNA, C/D box 87 Neighboring gene small nucleolar RNA host gene 6 Neighboring gene protein phosphatase 1, regulatory subunit 42 Neighboring gene STARR-seq mESC enhancer starr_00178 Neighboring gene STARR-seq mESC enhancer starr_00179 Neighboring gene predicted gene, 24674 Neighboring gene COP9 signalosome subunit 5 Neighboring gene centrosome and spindle pole associated protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A single-cell transcriptomic map of the developing Atoh1 lineage identifies neural fate decisions and neuronal diversity in the hindbrain. Butts JC, et al. Dev Cell, 2024 Aug 19. PMID 39106860
    2. Epigenetic repression of Cend1 by lysine-specific demethylase 1 is essential for murine heart development. Liu H, et al. iScience, 2024 Jan 19. PMID 38226173, Free PMC Article
    3. Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray. Nishimura M, et al. DNA Res, 2004 Oct 31. PMID 15747579
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in developmental process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    transcription factor 24

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001285425.2 → NP_001272354.1  transcription factor 24

      See identical proteins and their annotated locations for NP_001272354.1

      Status: VALIDATED

      Source sequence(s)
      AC102570
      Consensus CDS
      CCDS69862.1
      UniProtKB/TrEMBL
      V9GWT9
      Conserved Domains (1) summary
      cd19710
      Location:49 → 104
      bHLH_TS_TCF24; basic helix-loop-helix (bHLH) domain found in transcription factor 24 (TCF-24) and similar proteins

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      10030388..10038207 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006495431.5 → XP_006495494.1  transcription factor 24 isoform X1

      See identical proteins and their annotated locations for XP_006495494.1

      UniProtKB/TrEMBL
      V9GWT9
      Related
      ENSMUSP00000138827.2, ENSMUST00000185184.2
      Conserved Domains (1) summary
      cd19710
      Location:49 → 104
      bHLH_TS_TCF24; basic helix-loop-helix (bHLH) domain found in transcription factor 24 (TCF-24) and similar proteins
    Nucleotide Protein Strain
    Heading Accession and Version

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