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    EPHA7 EPH receptor A7 [ Gallus gallus (chicken) ]

    Gene ID: 395967, updated on 26-Nov-2024

    Summary

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    Official Symbol
    EPHA7provided by CGNC
    Official Full Name
    EPH receptor A7provided by CGNC
    Primary source
    CGNC:49580
    See related
    Ensembl:ENSGALG00010004127
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    CEPHA7
    Orthologs
    human mouse all
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    Genomic context

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    See EPHA7 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (73598654..73758206)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (73393092..73552665)

    Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121110332 Neighboring gene uncharacterized LOC121110343 Neighboring gene microRNA 1677 Neighboring gene uncharacterized LOC107053105 Neighboring gene uncharacterized LOC121110325 Neighboring gene U6 spliceosomal RNA

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. EphA7 receptor is expressed differentially at chicken prosomeric boundaries. García-Calero E, et al. Neuroscience, 2006 Sep 15. PMID 16844303
    2. The expression of chick EphA7 during segmentation of the central and peripheral nervous system. Araujo M, et al. Mech Dev, 1997 Nov. PMID 9431814
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. EphA7 receptor is expressed differentially at chicken prosomeric boundaries.
      Title: EphA7 receptor is expressed differentially at chicken prosomeric boundaries.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables transmembrane-ephrin receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in axon guidance IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in neuron projection IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    ephrin type-A receptor 7
    Names
    EK11
    EPH-like kinase 11
    Eph-like receptor tyrosine kinase
    cEK11
    tyrosine-protein kinase receptor CEPHA7
    NP_001384405.1
    NP_001384406.1
    NP_990414.1
    XP_040552779.1
    XP_040552780.1
    XP_040552783.1
    XP_040552784.1
    XP_046769140.1
    XP_046769141.1
    XP_046769142.1
    XP_046769143.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001397476.1 → NP_001384405.1  ephrin type-A receptor 7 isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000065
      UniProtKB/TrEMBL
      A0A8V0XLI2
      Related
      ENSGALP00010005648.1, ENSGALT00010009622.1
      Conserved Domains (6) summary
      cd09548
      Location:910 → 979
      SAM_EPH-A7; SAM domain of EPH-A7 subfamily of tyrosine kinase receptors
      cd10485
      Location:30 → 206
      EphR_LBD_A7; Ligand Binding Domain of Ephrin type-A Receptor 7
      cd00063
      Location:443 → 534
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05066
      Location:619 → 885
      PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
      pfam00041
      Location:333 → 427
      fn3; Fibronectin type III domain
      pfam14575
      Location:560 → 621
      EphA2_TM; Ephrin type-A receptor 2 transmembrane domain

    2. NM_001397477.1 → NP_001384406.1  ephrin type-A receptor 7 isoform 3 precursor

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000065
      UniProtKB/TrEMBL
      A0A8V0XG19
      Related
      ENSGALP00010005649.1, ENSGALT00010009623.1
      Conserved Domains (3) summary
      cd10485
      Location:30 → 206
      EphR_LBD_A7; Ligand Binding Domain of Ephrin type-A Receptor 7
      cd00063
      Location:443 → 534
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05066
      Location:623 → 889
      PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors

    3. NM_205083.2 → NP_990414.1  ephrin type-A receptor 7 isoform 1 precursor

      See identical proteins and their annotated locations for NP_990414.1

      Status: VALIDATED

      Source sequence(s)
      JAENSK010000065
      UniProtKB/Swiss-Prot
      O42422
      Conserved Domains (6) summary
      cd09548
      Location:914 → 983
      SAM_EPH-A7; SAM domain of EPH-A7 subfamily of tyrosine kinase receptors
      cd10485
      Location:30 → 206
      EphR_LBD_A7; Ligand Binding Domain of Ephrin type-A Receptor 7
      cd00063
      Location:443 → 534
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05066
      Location:623 → 889
      PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
      pfam00041
      Location:333 → 427
      fn3; Fibronectin type III domain
      pfam14575
      Location:562 → 623
      EphA2_TM; Ephrin type-A receptor 2 transmembrane domain

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      73598654..73758206
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040696845.2 → XP_040552779.1  ephrin type-A receptor 7 isoform X1

      UniProtKB/TrEMBL
      A0A8V0XBZ6
      Related
      ENSGALP00010005650.1, ENSGALT00010009624.1
      Conserved Domains (4) summary
      cd10485
      Location:30 → 206
      EphR_LBD_A7; Ligand Binding Domain of Ephrin type-A Receptor 7
      cd00063
      Location:443 → 534
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05066
      Location:623 → 889
      PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
      cl15755
      Location:914 → 956
      SAM_superfamily; SAM (Sterile alpha motif )

    2. XM_040696846.2 → XP_040552780.1  ephrin type-A receptor 7 isoform X2

      Conserved Domains (4) summary
      cd10485
      Location:30 → 206
      EphR_LBD_A7; Ligand Binding Domain of Ephrin type-A Receptor 7
      cd00063
      Location:443 → 534
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05066
      Location:619 → 885
      PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
      cl15755
      Location:910 → 952
      SAM_superfamily; SAM (Sterile alpha motif )

    3. XM_040696849.2 → XP_040552783.1  ephrin type-A receptor 7 isoform X3

      Conserved Domains (4) summary
      cd00063
      Location:328 → 419
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cd05066
      Location:508 → 774
      PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
      cl02704
      Location:30 → 72
      EphR_LBD; Ligand Binding Domain of Ephrin Receptors
      cl15755
      Location:799 → 841
      SAM_superfamily; SAM (Sterile alpha motif )

    4. XM_040696850.2 → XP_040552784.1  ephrin type-A receptor 7 isoform X4

      Conserved Domains (2) summary
      cd00063
      Location:332 → 438
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cl02704
      Location:30 → 206
      EphR_LBD; Ligand Binding Domain of Ephrin Receptors

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      73393092..73552665
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046913184.1 → XP_046769140.1  ephrin type-A receptor 7 isoform X1

    2. XM_046913185.1 → XP_046769141.1  ephrin type-A receptor 7 isoform X2

    3. XM_046913186.1 → XP_046769142.1  ephrin type-A receptor 7 isoform X3

    4. XM_046913187.1 → XP_046769143.1  ephrin type-A receptor 7 isoform X4

    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O42422.1 GenPept UniProtKB/Swiss-Prot:O42422

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.