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    Zfp930 zinc finger protein 930 [ Mus musculus (house mouse) ]

    Gene ID: 234358, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Zfp930provided by MGI
    Official Full Name
    zinc finger protein 930provided by MGI
    Primary source
    MGI:MGI:2675306
    See related
    Ensembl:ENSMUSG00000059897 AllianceGenome:MGI:2675306
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in ductus deferens; metanephros; and testis. Orthologous to several human genes including ZNF117 (zinc finger protein 117); ZNF490 (zinc finger protein 490); and ZNF708 (zinc finger protein 708). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in CNS E11.5 (RPKM 2.4), liver E14 (RPKM 2.2) and 23 other tissues See more
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    Genomic context

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    See Zfp930 in Genome Data Viewer
    Location:
    8 B3.3; 8 33.88 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (69661701..69683188)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (69209018..69230539)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene leucine zipper, putative tumor suppressor 1 Neighboring gene predicted gene, 39187 Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:71700363-71700564 Neighboring gene STARR-positive B cell enhancer ABC_E6640 Neighboring gene STARR-positive B cell enhancer ABC_E3775 Neighboring gene STARR-seq mESC enhancer starr_21725 Neighboring gene predicted gene, 39188 Neighboring gene predicted gene, 33178 Neighboring gene membrane-associated ring finger (C3HC4) 5 pseudogene Neighboring gene STARR-seq mESC enhancer starr_21726 Neighboring gene STARR-positive B cell enhancer ABC_E2263 Neighboring gene STARR-seq mESC enhancer starr_21728 Neighboring gene zinc finger protein 781A Neighboring gene STARR-seq mESC enhancer starr_21730

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells. Samudyata, et al. Exp Cell Res, 2019 Aug 1. PMID 31077711, Free PMC Article
    2. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
    3. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
    4. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
    5. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (2) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC234358

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013379.3 → NP_001013397.2  uncharacterized protein LOC234358 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC114995, AC117621
      Consensus CDS
      CCDS85546.1
      UniProtKB/TrEMBL
      A0A1D5RM15
      Related
      ENSMUSP00000148587.2, ENSMUST00000212681.2
      Conserved Domains (5) summary
      smart00349
      Location:4 → 49
      KRAB; krueppel associated box
      COG5048
      Location:72 → 432
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:216 → 236
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:4 → 43
      KRAB; KRAB box
      pfam13465
      Location:256 → 281
      zf-H2C2_2; Zinc-finger double domain

    2. NM_001426649.1 → NP_001413578.1  uncharacterized protein LOC234358 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC114995, AC117621

    3. NM_001426650.1 → NP_001413579.1  uncharacterized protein LOC234358 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC114995, AC117621

    4. NM_001426651.1 → NP_001413580.1  uncharacterized protein LOC234358 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC114995, AC117621
      Related
      ENSMUSP00000105845.2, ENSMUST00000110216.2

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      69661701..69683188
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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