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    Golt1b golgi transport 1B [ Mus musculus (house mouse) ]

    Gene ID: 66964, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Golt1bprovided by MGI
    Official Full Name
    golgi transport 1Bprovided by MGI
    Primary source
    MGI:MGI:1914214
    See related
    Ensembl:ENSMUSG00000030245 AllianceGenome:MGI:1914214
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    CGI-141; 2310061A22Rik
    Summary
    Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport; protein transport; and retrograde transport, endosome to Golgi. Predicted to be located in Golgi membrane and cytosol. Predicted to be part of protein-containing complex. Predicted to be active in endoplasmic reticulum and membrane. Is expressed in orbito-sphenoid. Orthologous to human GOLT1B (golgi transport 1B). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Ubiquitous expression in placenta adult (RPKM 11.2), limb E14.5 (RPKM 10.4) and 25 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Golt1b in Genome Data Viewer
    Location:
    6 G2; 6 73.98 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (142332929..142349584)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (142387211..142413835)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene solute carrier organic anion transporter family, member 1a5 Neighboring gene 60S ribosomal protein L18 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E6502 Neighboring gene pyridine nucleotide-disulphide oxidoreductase domain 1 Neighboring gene RecQ protein-like Neighboring gene STARR-positive B cell enhancer ABC_E1716 Neighboring gene spexin hormone Neighboring gene glycogen synthase 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. ZMPSTE24 defends against influenza and other pathogenic viruses. Fu B, et al. J Exp Med, 2017 Apr 3. PMID 28246125, Free PMC Article
    2. Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors. Kim H, et al. Cell, 2018 Dec 13. PMID 30550785, Free PMC Article
    3. Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function. Zhang T, et al. Sci Rep, 2017 Apr 5. PMID 28378742, Free PMC Article
    4. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
    5. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (3) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in retrograde transport, endosome to Golgi IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    vesicle transport protein GOT1B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001417653.1 → NP_001404582.1  vesicle transport protein GOT1B isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC142413

    2. NM_001417654.1 → NP_001404583.1  vesicle transport protein GOT1B isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC142413

    3. NM_001417655.1 → NP_001404584.1  vesicle transport protein GOT1B isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC142413

    4. NM_025872.5 → NP_080148.1  vesicle transport protein GOT1B isoform 3

      See identical proteins and their annotated locations for NP_080148.1

      Status: VALIDATED

      Source sequence(s)
      AC142413
      Consensus CDS
      CCDS20682.1
      UniProtKB/Swiss-Prot
      Q9CR60
      Related
      ENSMUSP00000032372.7, ENSMUST00000032372.7
      Conserved Domains (1) summary
      cl02130
      Location:4 → 120
      Got1; Got1/Sft2-like family

    RNA

    1. NR_184553.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC142413

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      142332929..142349584
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036152265.1 → XP_036008158.1  vesicle transport protein GOT1B isoform X1

      Conserved Domains (1) summary
      cl02130
      Location:4 → 120
      Got1; Got1/Sft2-like family
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9CR60.1 GenPept UniProtKB/Swiss-Prot:Q9CR60

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
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