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    Map7d3 MAP7 domain containing 3 [ Mus musculus (house mouse) ]

    Gene ID: 320923, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Map7d3provided by MGI
    Official Full Name
    MAP7 domain containing 3provided by MGI
    Primary source
    MGI:MGI:2445051
    See related
    Ensembl:ENSMUSG00000067878 AllianceGenome:MGI:2445051
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mtap7d3; 4933424A10Rik
    Summary
    Predicted to enable microtubule binding activity. Predicted to be involved in microtubule polymerization. Predicted to be located in cytoplasm and spindle. Predicted to be active in microtubule cytoskeleton. Orthologous to human MAP7D3 (MAP7 domain containing 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    human all
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    Genomic context

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    See Map7d3 in Genome Data Viewer
    Location:
    X A6; X 30.16 cM
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (55840193..55867866, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (56794833..56822490, complement)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 26312 Neighboring gene four and a half LIM domains 1 Neighboring gene predicted gene, 23258 Neighboring gene STARR-seq mESC enhancer starr_47209 Neighboring gene STARR-seq mESC enhancer starr_47210 Neighboring gene adhesion G protein-coupled receptor G4 Neighboring gene bombesin-like receptor 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Human X chromosome exome sequencing identifies BCORL1 as contributor to spermatogenesis. Lu C, et al. J Med Genet, 2021 Jan. PMID 32376790
    2. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
    3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Human X chromosome exome sequencing identifies BCORL1 as contributor to spermatogenesis.
      Title: Human X chromosome exome sequencing identifies BCORL1 as contributor to spermatogenesis.
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables microtubule binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables microtubule binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables tubulin binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables tubulin binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in microtubule cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in microtubule cytoskeleton organization ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in microtubule cytoskeleton organization ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in microtubule polymerization ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in microtubule polymerization ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in microtubule cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in spindle IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    MAP7 domain-containing protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177293.3 → NP_796267.2  MAP7 domain-containing protein 3

      See identical proteins and their annotated locations for NP_796267.2

      Status: VALIDATED

      Source sequence(s)
      AK030211, AK048385, BB610806, BC096764
      Consensus CDS
      CCDS40982.1
      UniProtKB/Swiss-Prot
      A2AEY4, Q0VF65, Q8C7V9, Q8C857, Q8CDD4
      Related
      ENSMUSP00000110414.2, ENSMUST00000114766.8
      Conserved Domains (2) summary
      pfam05672
      Location:558 → 657
      MAP7; MAP7 (E-MAP-115) family
      pfam11208
      Location:62 → 129
      DUF2992; Protein of unknown function (DUF2992)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      55840193..55867866 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006528089.3 → XP_006528152.1  MAP7 domain-containing protein 3 isoform X2

      Conserved Domains (3) summary
      PRK09510
      Location:114 → 193
      tolA; cell envelope integrity inner membrane protein TolA; Provisional
      pfam05672
      Location:614 → 711
      MAP7; MAP7 (E-MAP-115) family
      pfam16598
      Location:44 → 114
      Edc3_linker; Linker region of enhancer of mRNA-decapping protein 3

    2. XM_036161989.1 → XP_036017882.1  MAP7 domain-containing protein 3 isoform X3

      Conserved Domains (2) summary
      PRK09510
      Location:114 → 193
      tolA; cell envelope integrity inner membrane protein TolA; Provisional
      NF033875
      Location:530 → 795
      Agg_substance; LPXTG-anchored aggregation substance

    3. XM_006528088.3 → XP_006528151.1  MAP7 domain-containing protein 3 isoform X1

      Conserved Domains (3) summary
      PRK09510
      Location:114 → 193
      tolA; cell envelope integrity inner membrane protein TolA; Provisional
      pfam05672
      Location:614 → 711
      MAP7; MAP7 (E-MAP-115) family
      pfam16598
      Location:44 → 114
      Edc3_linker; Linker region of enhancer of mRNA-decapping protein 3

    RNA

    1. XR_878106.2 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A2AEY4.1 GenPept UniProtKB/Swiss-Prot:A2AEY4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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