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    Spmip2 sperm microtubule inner protein 2 [ Mus musculus (house mouse) ]

    Gene ID: 100233207, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Spmip2provided by MGI
    Official Full Name
    sperm microtubule inner protein 2provided by MGI
    Primary source
    MGI:MGI:4936993
    See related
    Ensembl:ENSMUSG00000091685 AllianceGenome:MGI:4936993
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm17359
    Summary
    Is expressed in ductus deferens and testis. Orthologous to human SPMIP2 (sperm microtubule inner protein 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Restricted expression toward testis adult (RPKM 87.6) See more
    Orthologs
    human all
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    Genomic context

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    See Spmip2 in Genome Data Viewer
    Location:
    3 E3; 3 34.91 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (79243937..79371436)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (79336630..79464129)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene Rap guanine nucleotide exchange factor (GEF) 2 Neighboring gene RIKEN cDNA 6430573P05 gene Neighboring gene STARR-seq mESC enhancer starr_07995 Neighboring gene predicted gene, 40072 Neighboring gene STARR-seq mESC enhancer starr_07997 Neighboring gene STARR-seq mESC enhancer starr_07998 Neighboring gene STARR-seq mESC enhancer starr_07999 Neighboring gene STARR-seq mESC enhancer starr_08000 Neighboring gene folliculin interacting protein 2 Neighboring gene STARR-seq mESC enhancer starr_08002 Neighboring gene RIKEN cDNA 4930589L23 gene Neighboring gene STARR-seq mESC enhancer starr_08006 Neighboring gene peptidylprolyl isomerase D (cyclophilin D) Neighboring gene electron transferring flavoprotein, dehydrogenase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. High-throughput discovery of novel developmental phenotypes. Dickinson ME, et al. Nature, 2016 Sep 22. PMID 27626380, Free PMC Article
    2. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
    3. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (2) 

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    protein SPMIP2
    Names
    sperm associated microtubule inner protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001142953.2 → NP_001136425.1  protein SPMIP2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC142502
      Consensus CDS
      CCDS50933.1
      UniProtKB/TrEMBL
      E9QAV2
      Related
      ENSMUSP00000130702.2, ENSMUST00000164216.6
      Conserved Domains (1) summary
      pfam15123
      Location:21 → 132
      DUF4562; Domain of unknown function (DUF4562)

    2. NM_001370773.1 → NP_001357702.1  protein SPMIP2 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC142502
      Consensus CDS
      CCDS89638.1
      UniProtKB/TrEMBL
      A0A0G2JEB7
      Related
      ENSMUSP00000142709.2, ENSMUST00000199658.2
      Conserved Domains (1) summary
      pfam15123
      Location:21 → 117
      DUF4562; Domain of unknown function (DUF4562)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      79243937..79371436
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030252332.1 → XP_030108192.1  protein SPMIP2 isoform X1

    2. XM_011239979.2 → XP_011238281.1  protein SPMIP2 isoform X1

      See identical proteins and their annotated locations for XP_011238281.1

    3. XM_011239980.3 → XP_011238282.1  protein SPMIP2 isoform X1

      See identical proteins and their annotated locations for XP_011238282.1

    Nucleotide Protein
    Heading Accession and Version

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