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    Gm14496 predicted gene 14496 [ Mus musculus (house mouse) ]

    Gene ID: 672125, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Gm14496provided by MGI
    Official Full Name
    predicted gene 14496provided by MGI
    Primary source
    MGI:MGI:3769929
    See related
    Ensembl:ENSMUSG00000098505 AllianceGenome:MGI:3769929
    Gene type
    protein coding
    RefSeq status
    INFERRED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable G protein-coupled receptor activity. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Gm14496 in Genome Data Viewer
    Location:
    2 H4; 2 103.9 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (181633019..181642880)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (181991226..182001087)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_06759 Neighboring gene predicted gene, 40034 Neighboring gene STARR-positive B cell enhancer mm9_chr2:181667029-181667330 Neighboring gene predicted gene, 40035 Neighboring gene STARR-seq mESC enhancer starr_06762 Neighboring gene STARR-seq mESC enhancer starr_06763 Neighboring gene STARR-seq mESC enhancer starr_06764

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
    2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    vomeronasal 2, receptor family protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001205282.1 → NP_001192211.1  vomeronasal 2, receptor family protein precursor

      Status: INFERRED

      Source sequence(s)
      AL928734, CU207327
      Consensus CDS
      CCDS57205.1
      UniProtKB/TrEMBL
      A0A494B9E1, K7N5U4
      Related
      ENSMUSP00000071670.7, ENSMUST00000071760.8
      Conserved Domains (3) summary
      cd06365
      Location:41 → 500
      PBP1_Pheromone_receptor; Ligand-binding domain of the V2R phermone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily
      pfam00003
      Location:596 → 830
      7tm_3; 7 transmembrane sweet-taste receptor of 3 GCPR
      pfam07562
      Location:509 → 561
      NCD3G; Nine Cysteines Domain of family 3 GPCR

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      181633019..181642880
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030251981.1 → XP_030107841.1  vomeronasal 2, receptor family protein isoform X3

      UniProtKB/TrEMBL
      A0A494B9E1
      Conserved Domains (2) summary
      cd15283
      Location:541 → 791
      7tmC_V2R_pheromone; vomeronasal type-2 pheromone receptors, member of the class C family of seven-transmembrane G protein-coupled receptors
      cd06365
      Location:46 → 500
      PBP1_pheromone_receptor; Ligand-binding domain of the V2R pheromone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily

    2. XM_030251980.1 → XP_030107840.1  vomeronasal 2, receptor family protein isoform X2

      UniProtKB/TrEMBL
      A0A494B9E1, A0A494BAK9
      Related
      ENSMUSP00000158134.2, ENSMUST00000236373.2
      Conserved Domains (3) summary
      cd15283
      Location:581 → 831
      7tmC_V2R_pheromone; vomeronasal type-2 pheromone receptors, member of the class C family of seven-transmembrane G protein-coupled receptors
      pfam07562
      Location:508 → 561
      NCD3G; Nine Cysteines Domain of family 3 GPCR
      cd06365
      Location:46 → 500
      PBP1_pheromone_receptor; Ligand-binding domain of the V2R pheromone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily

    3. XM_030251979.1 → XP_030107839.1  vomeronasal 2, receptor family protein isoform X1

      UniProtKB/TrEMBL
      A0A494B9E1
      Conserved Domains (3) summary
      cd15283
      Location:583 → 833
      7tmC_V2R_pheromone; vomeronasal type-2 pheromone receptors, member of the class C family of seven-transmembrane G protein-coupled receptors
      pfam07562
      Location:510 → 563
      NCD3G; Nine Cysteines Domain of family 3 GPCR
      cd06365
      Location:46 → 500
      PBP1_pheromone_receptor; Ligand-binding domain of the V2R pheromone receptor, a member of the family C receptors within the G-protein coupled receptor superfamily

    4. XM_036162507.1 → XP_036018400.1  vomeronasal 2, receptor family protein isoform X4

      UniProtKB/TrEMBL
      A0A494B9E1
      Related
      ENSMUSP00000157614.2, ENSMUST00000184507.3
      Conserved Domains (3) summary
      cd15283
      Location:506 → 756
      7tmC_V2R_pheromone; vomeronasal type-2 pheromone receptors, member of the class C family of seven-transmembrane G protein-coupled receptors
      pfam07562
      Location:433 → 486
      NCD3G; Nine Cysteines Domain of family 3 GPCR
      cl10011
      Location:46 → 442
      Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily

    5. XM_017319216.1 → XP_017174705.1  vomeronasal 2, receptor family protein isoform X5

      Conserved Domains (1) summary
      cl10011
      Location:46 → 431
      Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily

    6. XM_017319217.1 → XP_017174706.1  vomeronasal 2, receptor family protein isoform X6

      Conserved Domains (1) summary
      cl10011
      Location:46 → 432
      Periplasmic_Binding_Protein_type1; Type 1 periplasmic binding fold superfamily
    Nucleotide Protein Strain
    Heading Accession and Version

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