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    Sec61b SEC61 translocon subunit beta [ Mus musculus (house mouse) ]

    Gene ID: 66212, updated on 9-Dec-2024

    Summary

    Official Symbol
    Sec61bprovided by MGI
    Official Full Name
    SEC61 translocon subunit betaprovided by MGI
    Primary source
    MGI:MGI:1913462
    See related
    Ensembl:ENSMUSG00000053317 AllianceGenome:MGI:1913462
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1190006C12Rik
    Summary
    Enables ribosome binding activity. Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane, translocation; post-translational protein targeting to membrane, translocation; and retrograde protein transport, ER to cytosol. Located in endoplasmic reticulum quality control compartment. Orthologous to human SEC61B (SEC61 translocon subunit beta). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in adrenal adult (RPKM 203.0), colon adult (RPKM 171.1) and 27 other tissues See more
    Orthologs
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    Genomic context

    See Sec61b in Genome Data Viewer
    Location:
    4 B1; 4 26.03 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (47474661..47483233)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (47474661..47483233)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_10143 Neighboring gene microfibrillar-associated protein 1B pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E3491 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:47487387-47487624 Neighboring gene ALG2 alpha-1,3/1,6-mannosyltransferase Neighboring gene predicted gene, 42283 Neighboring gene STARR-seq mESC enhancer starr_10145 Neighboring gene STARR-seq mESC enhancer starr_10146 Neighboring gene predicted gene, 42284 Neighboring gene predicted gene, 32487

    Genomic regions, transcripts, and products

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    General gene information

    Clone Names

    • MGC102034

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables epidermal growth factor binding  
    enables epidermal growth factor binding  
    enables guanyl-nucleotide exchange factor activity  
    enables protein binding PubMed 
    enables ribosome binding PubMed 
    enables ribosome binding  
    Component Evidence Code Pubs
    part_of Sec61 translocon complex  
    part_of Sec61 translocon complex  
    located_in endoplasmic reticulum PubMed 
    located_in endoplasmic reticulum  
    located_in endoplasmic reticulum membrane  
    located_in endoplasmic reticulum membrane  
    located_in endoplasmic reticulum quality control compartment PubMed 
    located_in endoplasmic reticulum quality control compartment  
    is_active_in membrane  
    located_in membrane PubMed 

    General protein information

    Preferred Names
    protein transport protein Sec61 subunit beta
    Names
    Sec61 beta subunit

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_024171.2NP_077133.1  protein transport protein Sec61 subunit beta

      See identical proteins and their annotated locations for NP_077133.1

      Status: PROVISIONAL

      Source sequence(s)
      AK004505
      Consensus CDS
      CCDS38759.1
      UniProtKB/Swiss-Prot
      Q9CQS8
      Related
      ENSMUSP00000067681.6, ENSMUST00000065678.6
      Conserved Domains (1) summary
      pfam03911
      Location:5491
      Sec61_beta; Sec61beta family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      47474661..47483233
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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