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    Tenm3 teneurin transmembrane protein 3 [ Mus musculus (house mouse) ]

    Gene ID: 23965, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Tenm3provided by MGI
    Official Full Name
    teneurin transmembrane protein 3provided by MGI
    Primary source
    MGI:MGI:1345183
    See related
    Ensembl:ENSMUSG00000031561 AllianceGenome:MGI:1345183
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Odz1; Odz3; Ten-m3; mKIAA1455; 2610100B16Rik
    Summary
    Enables protein heterodimerization activity and protein homodimerization activity. Involved in several processes, including homophilic cell adhesion via plasma membrane adhesion molecules; regulation of homophilic cell adhesion; and synaptic membrane adhesion. Located in plasma membrane. Is active in glutamatergic synapse and presynaptic active zone membrane. Is expressed in several structures, including alimentary system; branchial arch; genitourinary system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in cocaine dependence. Orthologous to human TENM3 (teneurin transmembrane protein 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in limb E14.5 (RPKM 6.8), CNS E11.5 (RPKM 6.4) and 20 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Tenm3 in Genome Data Viewer
    Location:
    8 B1.2- B1.3; 8 27.02 cM
    Exon count:
    49
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (48678700..51370255, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (48225665..49522824, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 32194 Neighboring gene predicted gene, 51559 Neighboring gene predicted gene, 32923 Neighboring gene predicted gene, 51531 Neighboring gene STARR-seq mESC enhancer starr_21446 Neighboring gene STARR-seq mESC enhancer starr_21450 Neighboring gene STARR-seq mESC enhancer starr_21451 Neighboring gene STARR-seq mESC enhancer starr_21453 Neighboring gene predicted gene, 39178 Neighboring gene predicted gene, 19744 Neighboring gene STARR-seq mESC enhancer starr_21457 Neighboring gene predicted gene, 25830 Neighboring gene STARR-seq mESC enhancer starr_21458 Neighboring gene RIKEN cDNA 4930555F03 gene Neighboring gene STARR-seq mESC enhancer starr_21460 Neighboring gene STARR-seq mESC enhancer starr_21462 Neighboring gene STARR-seq mESC enhancer starr_21463 Neighboring gene STARR-seq mESC enhancer starr_21464 Neighboring gene STARR-seq mESC enhancer starr_21465 Neighboring gene STARR-seq mESC enhancer starr_21466 Neighboring gene STARR-seq mESC enhancer starr_21467 Neighboring gene STARR-seq mESC enhancer starr_21468 Neighboring gene predicted gene 2516 Neighboring gene predicted gene, 23986 Neighboring gene STARR-seq mESC enhancer starr_21469 Neighboring gene STARR-seq mESC enhancer starr_21470 Neighboring gene STARR-seq mESC enhancer starr_21472 Neighboring gene predicted gene, 32975 Neighboring gene chaperonin containing Tcp1, subunit 6a (zeta) pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Teneurin-3 regulates the generation of non-image-forming visual circuitry and responsiveness to light in the suprachiasmatic nucleus.
      Title: Teneurin-3 regulates the generation of non-image-forming visual circuitry and responsiveness to light in the suprachiasmatic nucleus.
    2. Ten-m3 plays a role in the formation of thalamostriatal projections.
      Title: Ten-m3 plays a role in the formation of thalamostriatal projections.
    3. Ten-m/Odz3 regulates migration and differentiation of chondrogenic ATDC5 cells via RhoA-mediated actin reorganization.
      Title: Ten-m/Odz3 regulates migration and differentiation of chondrogenic ATDC5 cells via RhoA-mediated actin reorganization.
    4. Reciprocal repulsions instruct the precise assembly of parallel hippocampal networks.
      Title: Reciprocal repulsions instruct the precise assembly of parallel hippocampal networks.
    5. Ipsilateral retinal axons in Ten-m3 knockout mice are mismapped as a consequence of early axonal guidance defects. The aberrant invasion of the ventral-most region of the dorsal lateral geniculate nucleus by ipsilateral retinal axons in Ten-m3 knockouts suggested changes in the expression of other axonal guidance molecules, particularly members of the EphA-ephrinA family.
      Title: Downstream mediators of Ten-m3 signalling in the developing visual pathway.
    6. Results demonstrate that Ten-m3 plays a key role in directing the formation of thalamostriatal circuitry, the first molecular candidate reported to regulate connectivity within this pathway
      Title: The glycoprotein Ten-m3 mediates topography and patterning of thalamostriatal projections from the parafascicular nucleus in mice.
    7. This study demonstrated that ipsilateral inputs to V1 are expanded and mismatched with respect to contralateral inputs in Ten-m3 knockout mice.
      Title: Deletion of Ten-m3 induces the formation of eye dominance domains in mouse visual cortex.
    8. Ten-m3 plays a critical role in this process and is particularly important for the mapping of the ipsilateral retinocollicular pathway.
      Title: Ten-m3 is required for the development of topography in the ipsilateral retinocollicular pathway.
    9. Ten_m3 regulates the alignment of ipsilateral and contralateral projections. It is expressed in a gradient in the developing visual pathway, which is consistently highest in regions that represent dorsal visual field
      Title: Ten_m3 regulates eye-specific patterning in the mammalian visual pathway and is required for binocular vision.
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables cell adhesion molecule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein heterodimerization activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables protein heterodimerization activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    NOT enables protein homodimerization activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein homodimerization activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in camera-type eye morphogenesis ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in cell differentiation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in homophilic cell adhesion via plasma membrane adhesion molecules IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in neuron development IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of neuron projection development IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in positive regulation of neuron projection development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    NOT involved_in regulation of homophilic cell adhesion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of homophilic cell adhesion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in synaptic membrane adhesion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in axon IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in glutamatergic synapse IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in neuron projection IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    is_active_in presynaptic active zone membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    teneurin-3
    Names
    odd Oz/ten-m homolog 3
    protein Odd Oz/ten-m homolog 3
    ten-3
    tenascin-M3

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001145937.1 → NP_001139409.1  teneurin-3 isoform 2

      See identical proteins and their annotated locations for NP_001139409.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks two coding exons, as compared to variant 1. The resulting isoform (2) lacks two internal segments and have the same N- and C-termini, as compared to isoform 1.
      Source sequence(s)
      AC164420, BC145284, BI989409, BP758815
      Consensus CDS
      CCDS85538.1
      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      UniProtKB/TrEMBL
      B7ZNJ5
      Related
      ENSMUSP00000140141.3, ENSMUST00000190840.8
      Conserved Domains (9) summary
      COG3209
      Location:1903 → 2414
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1175 → 1210
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1823 → 1863
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:2318 → 2392
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1146 → 1498
      NHL; NHL repeat unit of beta-propeller proteins
      pfam05593
      Location:1615 → 1646
      RHS_repeat; RHS Repeat
      pfam06484
      Location:11 → 308
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2615 → 2692
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:466 → 792
      exchanger_TraA; outer membrane exchange protein TraA

    2. NM_011857.3 → NP_035987.3  teneurin-3 isoform 1

      See identical proteins and their annotated locations for NP_035987.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      AC125536, AC126689, AC132120, AC140446, AC164420
      Consensus CDS
      CCDS22303.1
      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      UniProtKB/TrEMBL
      G3X907
      Related
      ENSMUSP00000033965.7, ENSMUST00000033965.14
      Conserved Domains (9) summary
      COG3209
      Location:1919 → 2430
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1184 → 1223
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1839 → 1879
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:2334 → 2408
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1155 → 1514
      NHL; NHL repeat unit of beta-propeller proteins
      pfam05593
      Location:1631 → 1662
      RHS_repeat; RHS Repeat
      pfam06484
      Location:11 → 308
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2631 → 2708
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:466 → 801
      exchanger_TraA; outer membrane exchange protein TraA

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      48678700..51370255 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036153998.1 → XP_036009891.1  teneurin-3 isoform X11

      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      UniProtKB/TrEMBL
      G3X907
      Conserved Domains (9) summary
      COG3209
      Location:1919 → 2430
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1184 → 1223
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1839 → 1879
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:2334 → 2408
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1155 → 1514
      NHL; NHL repeat unit of beta-propeller proteins
      pfam05593
      Location:1631 → 1662
      RHS_repeat; RHS Repeat
      pfam06484
      Location:11 → 308
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2631 → 2708
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:466 → 801
      exchanger_TraA; outer membrane exchange protein TraA

    2. XM_006509405.4 → XP_006509468.1  teneurin-3 isoform X9

      See identical proteins and their annotated locations for XP_006509468.1

      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      Conserved Domains (9) summary
      COG3209
      Location:1926 → 2437
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1191 → 1230
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1846 → 1886
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:2341 → 2415
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1162 → 1521
      NHL; NHL repeat unit of beta-propeller proteins
      pfam05593
      Location:1638 → 1669
      RHS_repeat; RHS Repeat
      pfam06484
      Location:11 → 308
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2638 → 2715
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:466 → 808
      exchanger_TraA; outer membrane exchange protein TraA

    3. XM_036153996.1 → XP_036009889.1  teneurin-3 isoform X9

      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      Conserved Domains (9) summary
      COG3209
      Location:1926 → 2437
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1191 → 1230
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1846 → 1886
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:2341 → 2415
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1162 → 1521
      NHL; NHL repeat unit of beta-propeller proteins
      pfam05593
      Location:1638 → 1669
      RHS_repeat; RHS Repeat
      pfam06484
      Location:11 → 308
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2638 → 2715
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:466 → 808
      exchanger_TraA; outer membrane exchange protein TraA

    4. XM_036153995.1 → XP_036009888.1  teneurin-3 isoform X9

      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      Conserved Domains (9) summary
      COG3209
      Location:1926 → 2437
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1191 → 1230
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1846 → 1886
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:2341 → 2415
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1162 → 1521
      NHL; NHL repeat unit of beta-propeller proteins
      pfam05593
      Location:1638 → 1669
      RHS_repeat; RHS Repeat
      pfam06484
      Location:11 → 308
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2638 → 2715
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:466 → 808
      exchanger_TraA; outer membrane exchange protein TraA

    5. XM_036154005.1 → XP_036009898.1  teneurin-3 isoform X14

      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      Conserved Domains (9) summary
      COG3209
      Location:1833 → 2344
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1098 → 1137
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1753 → 1793
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:2248 → 2322
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1069 → 1428
      NHL; NHL repeat unit of beta-propeller proteins
      pfam05593
      Location:1545 → 1576
      RHS_repeat; RHS Repeat
      pfam06484
      Location:11 → 215
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2545 → 2622
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:373 → 715
      exchanger_TraA; outer membrane exchange protein TraA

    6. XM_036153992.1 → XP_036009885.1  teneurin-3 isoform X9

      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      Conserved Domains (9) summary
      COG3209
      Location:1926 → 2437
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1191 → 1230
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1846 → 1886
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:2341 → 2415
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1162 → 1521
      NHL; NHL repeat unit of beta-propeller proteins
      pfam05593
      Location:1638 → 1669
      RHS_repeat; RHS Repeat
      pfam06484
      Location:11 → 308
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2638 → 2715
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:466 → 808
      exchanger_TraA; outer membrane exchange protein TraA

    7. XM_036153993.1 → XP_036009886.1  teneurin-3 isoform X9

      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      Conserved Domains (9) summary
      COG3209
      Location:1926 → 2437
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1191 → 1230
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1846 → 1886
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:2341 → 2415
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1162 → 1521
      NHL; NHL repeat unit of beta-propeller proteins
      pfam05593
      Location:1638 → 1669
      RHS_repeat; RHS Repeat
      pfam06484
      Location:11 → 308
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2638 → 2715
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:466 → 808
      exchanger_TraA; outer membrane exchange protein TraA

    8. XM_036153994.1 → XP_036009887.1  teneurin-3 isoform X9

      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      Conserved Domains (9) summary
      COG3209
      Location:1926 → 2437
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1191 → 1230
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1846 → 1886
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:2341 → 2415
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1162 → 1521
      NHL; NHL repeat unit of beta-propeller proteins
      pfam05593
      Location:1638 → 1669
      RHS_repeat; RHS Repeat
      pfam06484
      Location:11 → 308
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2638 → 2715
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:466 → 808
      exchanger_TraA; outer membrane exchange protein TraA

    9. XM_036154006.1 → XP_036009899.1  teneurin-3 isoform X14

      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      Conserved Domains (9) summary
      COG3209
      Location:1833 → 2344
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1098 → 1137
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1753 → 1793
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:2248 → 2322
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1069 → 1428
      NHL; NHL repeat unit of beta-propeller proteins
      pfam05593
      Location:1545 → 1576
      RHS_repeat; RHS Repeat
      pfam06484
      Location:11 → 215
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2545 → 2622
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:373 → 715
      exchanger_TraA; outer membrane exchange protein TraA

    10. XM_036154007.1 → XP_036009900.1  teneurin-3 isoform X14

      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      Conserved Domains (9) summary
      COG3209
      Location:1833 → 2344
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1098 → 1137
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1753 → 1793
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:2248 → 2322
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1069 → 1428
      NHL; NHL repeat unit of beta-propeller proteins
      pfam05593
      Location:1545 → 1576
      RHS_repeat; RHS Repeat
      pfam06484
      Location:11 → 215
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2545 → 2622
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:373 → 715
      exchanger_TraA; outer membrane exchange protein TraA

    11. XM_036154002.1 → XP_036009895.1  teneurin-3 isoform X12

      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      Conserved Domains (9) summary
      COG3209
      Location:1910 → 2421
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1175 → 1214
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1830 → 1870
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:2325 → 2399
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1146 → 1505
      NHL; NHL repeat unit of beta-propeller proteins
      pfam05593
      Location:1622 → 1653
      RHS_repeat; RHS Repeat
      pfam06484
      Location:11 → 308
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2622 → 2699
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:466 → 792
      exchanger_TraA; outer membrane exchange protein TraA

    12. XM_036153999.1 → XP_036009892.1  teneurin-3 isoform X11

      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      UniProtKB/TrEMBL
      G3X907
      Conserved Domains (9) summary
      COG3209
      Location:1919 → 2430
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1184 → 1223
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1839 → 1879
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:2334 → 2408
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1155 → 1514
      NHL; NHL repeat unit of beta-propeller proteins
      pfam05593
      Location:1631 → 1662
      RHS_repeat; RHS Repeat
      pfam06484
      Location:11 → 308
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2631 → 2708
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:466 → 801
      exchanger_TraA; outer membrane exchange protein TraA

    13. XM_011242216.3 → XP_011240518.1  teneurin-3 isoform X9

      See identical proteins and their annotated locations for XP_011240518.1

      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      Conserved Domains (9) summary
      COG3209
      Location:1926 → 2437
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1191 → 1230
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1846 → 1886
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:2341 → 2415
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1162 → 1521
      NHL; NHL repeat unit of beta-propeller proteins
      pfam05593
      Location:1638 → 1669
      RHS_repeat; RHS Repeat
      pfam06484
      Location:11 → 308
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2638 → 2715
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:466 → 808
      exchanger_TraA; outer membrane exchange protein TraA

    14. XM_036154000.1 → XP_036009893.1  teneurin-3 isoform X11

      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      UniProtKB/TrEMBL
      G3X907
      Conserved Domains (9) summary
      COG3209
      Location:1919 → 2430
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1184 → 1223
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1839 → 1879
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:2334 → 2408
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1155 → 1514
      NHL; NHL repeat unit of beta-propeller proteins
      pfam05593
      Location:1631 → 1662
      RHS_repeat; RHS Repeat
      pfam06484
      Location:11 → 308
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2631 → 2708
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:466 → 801
      exchanger_TraA; outer membrane exchange protein TraA

    15. XM_011242218.4 → XP_011240520.1  teneurin-3 isoform X9

      See identical proteins and their annotated locations for XP_011240520.1

      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      Conserved Domains (9) summary
      COG3209
      Location:1926 → 2437
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1191 → 1230
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1846 → 1886
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:2341 → 2415
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1162 → 1521
      NHL; NHL repeat unit of beta-propeller proteins
      pfam05593
      Location:1638 → 1669
      RHS_repeat; RHS Repeat
      pfam06484
      Location:11 → 308
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2638 → 2715
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:466 → 808
      exchanger_TraA; outer membrane exchange protein TraA

    16. XM_011242217.4 → XP_011240519.1  teneurin-3 isoform X9

      See identical proteins and their annotated locations for XP_011240519.1

      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      Conserved Domains (9) summary
      COG3209
      Location:1926 → 2437
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1191 → 1230
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1846 → 1886
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:2341 → 2415
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1162 → 1521
      NHL; NHL repeat unit of beta-propeller proteins
      pfam05593
      Location:1638 → 1669
      RHS_repeat; RHS Repeat
      pfam06484
      Location:11 → 308
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2638 → 2715
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:466 → 808
      exchanger_TraA; outer membrane exchange protein TraA

    17. XM_036153997.1 → XP_036009890.1  teneurin-3 isoform X10

      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      Conserved Domains (9) summary
      COG3209
      Location:1925 → 2436
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1190 → 1229
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1845 → 1885
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:2340 → 2414
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1161 → 1520
      NHL; NHL repeat unit of beta-propeller proteins
      pfam05593
      Location:1637 → 1668
      RHS_repeat; RHS Repeat
      pfam06484
      Location:11 → 308
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2637 → 2714
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:466 → 807
      exchanger_TraA; outer membrane exchange protein TraA

    18. XM_006509404.5 → XP_006509467.1  teneurin-3 isoform X9

      See identical proteins and their annotated locations for XP_006509467.1

      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      Conserved Domains (9) summary
      COG3209
      Location:1926 → 2437
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1191 → 1230
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1846 → 1886
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:2341 → 2415
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1162 → 1521
      NHL; NHL repeat unit of beta-propeller proteins
      pfam05593
      Location:1638 → 1669
      RHS_repeat; RHS Repeat
      pfam06484
      Location:11 → 308
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2638 → 2715
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:466 → 808
      exchanger_TraA; outer membrane exchange protein TraA

    19. XM_036154003.1 → XP_036009896.1  teneurin-3 isoform X13

      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      UniProtKB/TrEMBL
      B7ZNJ5
      Conserved Domains (9) summary
      COG3209
      Location:1903 → 2414
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1175 → 1210
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1823 → 1863
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:2318 → 2392
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1146 → 1498
      NHL; NHL repeat unit of beta-propeller proteins
      pfam05593
      Location:1615 → 1646
      RHS_repeat; RHS Repeat
      pfam06484
      Location:11 → 308
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2615 → 2692
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:466 → 792
      exchanger_TraA; outer membrane exchange protein TraA

    20. XM_036154004.1 → XP_036009897.1  teneurin-3 isoform X14

      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      Conserved Domains (9) summary
      COG3209
      Location:1833 → 2344
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1098 → 1137
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1753 → 1793
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:2248 → 2322
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1069 → 1428
      NHL; NHL repeat unit of beta-propeller proteins
      pfam05593
      Location:1545 → 1576
      RHS_repeat; RHS Repeat
      pfam06484
      Location:11 → 215
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2545 → 2622
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:373 → 715
      exchanger_TraA; outer membrane exchange protein TraA

    21. XM_017312772.3 → XP_017168261.1  teneurin-3 isoform X9

      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      Conserved Domains (9) summary
      COG3209
      Location:1926 → 2437
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1191 → 1230
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1846 → 1886
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:2341 → 2415
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1162 → 1521
      NHL; NHL repeat unit of beta-propeller proteins
      pfam05593
      Location:1638 → 1669
      RHS_repeat; RHS Repeat
      pfam06484
      Location:11 → 308
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2638 → 2715
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:466 → 808
      exchanger_TraA; outer membrane exchange protein TraA

    22. XM_006509409.5 → XP_006509472.1  teneurin-3 isoform X15

      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      Conserved Domains (9) summary
      COG3209
      Location:1654 → 2165
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:919 → 958
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1574 → 1614
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:2069 → 2143
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:890 → 1249
      NHL; NHL repeat unit of beta-propeller proteins
      pfam05593
      Location:1366 → 1397
      RHS_repeat; RHS Repeat
      pfam06484
      Location:1 → 36
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2366 → 2443
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:194 → 536
      exchanger_TraA; outer membrane exchange protein TraA

    23. XM_030243526.2 → XP_030099386.1  teneurin-3 isoform X17

      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      Conserved Domains (11) summary
      COG3209
      Location:1647 → 2158
      RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]
      cd00054
      Location:481 → 510
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd05819
      Location:912 → 951
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1567 → 1607
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:2062 → 2136
      Rhs_assc_core; RHS repeat-associated core domain
      pfam07974
      Location:250 → 272
      EGF_2; EGF-like domain
      cl18310
      Location:883 → 1242
      NHL; NHL repeat unit of beta-propeller proteins
      pfam01414
      Location:377 → 435
      DSL; Delta serrate ligand
      pfam05593
      Location:1359 → 1392
      RHS_repeat; RHS Repeat
      pfam06484
      Location:1 → 36
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2359 → 2436
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin

    24. XM_030243525.2 → XP_030099385.1  teneurin-3 isoform X16

      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      Conserved Domains (11) summary
      COG3209
      Location:1653 → 2164
      RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]
      cd00054
      Location:487 → 516
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd05819
      Location:918 → 957
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1573 → 1613
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:2068 → 2142
      Rhs_assc_core; RHS repeat-associated core domain
      pfam07974
      Location:250 → 272
      EGF_2; EGF-like domain
      cl18310
      Location:889 → 1248
      NHL; NHL repeat unit of beta-propeller proteins
      pfam01414
      Location:377 → 435
      DSL; Delta serrate ligand
      pfam05593
      Location:1365 → 1398
      RHS_repeat; RHS Repeat
      pfam06484
      Location:1 → 36
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2365 → 2442
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin

    25. XM_030243528.2 → XP_030099388.1  teneurin-3 isoform X23

      Conserved Domains (9) summary
      COG3209
      Location:1298 → 1788
      RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]
      cd00054
      Location:111 → 140
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd05819
      Location:542 → 581
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1197 → 1237
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:1692 → 1766
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:513 → 872
      NHL; NHL repeat unit of beta-propeller proteins
      pfam05593
      Location:989 → 1022
      RHS_repeat; RHS Repeat
      pfam06484
      Location:1 → 36
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:1989 → 2066
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin

    26. XM_036153991.1 → XP_036009884.1  teneurin-3 isoform X8

      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      Conserved Domains (9) summary
      COG3209
      Location:1946 → 2457
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1218 → 1253
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1866 → 1906
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:2361 → 2435
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1189 → 1541
      NHL; NHL repeat unit of beta-propeller proteins
      pfam05593
      Location:1658 → 1689
      RHS_repeat; RHS Repeat
      pfam06484
      Location:192 → 351
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2658 → 2735
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:509 → 835
      exchanger_TraA; outer membrane exchange protein TraA

    27. XM_036153990.1 → XP_036009883.1  teneurin-3 isoform X7

      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      Conserved Domains (9) summary
      COG3209
      Location:1953 → 2464
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1218 → 1257
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1873 → 1913
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:2368 → 2442
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1189 → 1548
      NHL; NHL repeat unit of beta-propeller proteins
      pfam05593
      Location:1665 → 1696
      RHS_repeat; RHS Repeat
      pfam06484
      Location:192 → 351
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2665 → 2742
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:509 → 835
      exchanger_TraA; outer membrane exchange protein TraA

    28. XM_036153989.1 → XP_036009882.1  teneurin-3 isoform X6

      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      Conserved Domains (7) summary
      COG3209
      Location:1605 → 2466
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1227 → 1262
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2370 → 2444
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1198 → 1550
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:192 → 351
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2667 → 2744
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:509 → 844
      exchanger_TraA; outer membrane exchange protein TraA

    29. XM_036153987.1 → XP_036009880.1  teneurin-3 isoform X4

      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      Conserved Domains (7) summary
      COG3209
      Location:1612 → 2473
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1227 → 1266
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2377 → 2451
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1198 → 1557
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:192 → 351
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2674 → 2751
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:509 → 844
      exchanger_TraA; outer membrane exchange protein TraA

    30. XM_036153988.1 → XP_036009881.1  teneurin-3 isoform X5

      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      Conserved Domains (8) summary
      COG3209
      Location:1611 → 2472
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1233 → 1268
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2376 → 2450
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1204 → 1556
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:192 → 351
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2673 → 2750
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033662
      Location:834 → 864
      acid_disulf_rpt; acidic double-disulfide repeat
      NF033759
      Location:509 → 850
      exchanger_TraA; outer membrane exchange protein TraA

    31. XM_036153985.1 → XP_036009878.1  teneurin-3 isoform X2

      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      Conserved Domains (8) summary
      COG3209
      Location:1618 → 2479
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1233 → 1272
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2383 → 2457
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1204 → 1563
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:192 → 351
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2680 → 2757
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033662
      Location:834 → 864
      acid_disulf_rpt; acidic double-disulfide repeat
      NF033759
      Location:509 → 850
      exchanger_TraA; outer membrane exchange protein TraA

    32. XM_036153986.1 → XP_036009879.1  teneurin-3 isoform X3

      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      Conserved Domains (8) summary
      COG3209
      Location:1612 → 2473
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1234 → 1269
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2377 → 2451
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1205 → 1557
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:192 → 351
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2674 → 2751
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033662
      Location:835 → 865
      acid_disulf_rpt; acidic double-disulfide repeat
      NF033759
      Location:509 → 851
      exchanger_TraA; outer membrane exchange protein TraA

    33. XM_036153984.1 → XP_036009877.1  teneurin-3 isoform X1

      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      Conserved Domains (8) summary
      COG3209
      Location:1619 → 2480
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:1234 → 1273
      NHL; NHL repeat [structural motif]
      TIGR03696
      Location:2384 → 2458
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:1205 → 1564
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:192 → 351
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2681 → 2758
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033662
      Location:835 → 865
      acid_disulf_rpt; acidic double-disulfide repeat
      NF033759
      Location:509 → 851
      exchanger_TraA; outer membrane exchange protein TraA

    34. XM_036154011.1 → XP_036009904.1  teneurin-3 isoform X20

      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      Conserved Domains (10) summary
      COG3209
      Location:1592 → 2103
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd00054
      Location:426 → 455
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd05819
      Location:857 → 896
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1512 → 1552
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:2007 → 2081
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:828 → 1187
      NHL; NHL repeat unit of beta-propeller proteins
      pfam05593
      Location:1304 → 1335
      RHS_repeat; RHS Repeat
      pfam06484
      Location:192 → 351
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2304 → 2381
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033662
      Location:458 → 488
      acid_disulf_rpt; acidic double-disulfide repeat

    35. XM_036154010.1 → XP_036009903.1  teneurin-3 isoform X19

      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      Conserved Domains (10) summary
      COG3209
      Location:1598 → 2109
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd00054
      Location:432 → 461
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd05819
      Location:863 → 902
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1518 → 1558
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:2013 → 2087
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:834 → 1193
      NHL; NHL repeat unit of beta-propeller proteins
      pfam05593
      Location:1310 → 1341
      RHS_repeat; RHS Repeat
      pfam06484
      Location:192 → 351
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2310 → 2387
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033662
      Location:464 → 494
      acid_disulf_rpt; acidic double-disulfide repeat

    36. XM_036154009.1 → XP_036009902.1  teneurin-3 isoform X18

      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      Conserved Domains (10) summary
      COG3209
      Location:1599 → 2110
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd00054
      Location:433 → 462
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd05819
      Location:864 → 903
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1519 → 1559
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:2014 → 2088
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:835 → 1194
      NHL; NHL repeat unit of beta-propeller proteins
      pfam05593
      Location:1311 → 1342
      RHS_repeat; RHS Repeat
      pfam06484
      Location:192 → 351
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2311 → 2388
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033662
      Location:465 → 495
      acid_disulf_rpt; acidic double-disulfide repeat

    37. XM_036154012.1 → XP_036009905.1  teneurin-3 isoform X21

      Conserved Domains (10) summary
      COG3209
      Location:1583 → 2094
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd00054
      Location:413 → 446
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd05819
      Location:848 → 887
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1503 → 1543
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:1998 → 2072
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:819 → 1178
      NHL; NHL repeat unit of beta-propeller proteins
      pfam05593
      Location:1295 → 1326
      RHS_repeat; RHS Repeat
      pfam06484
      Location:192 → 351
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2295 → 2372
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033662
      Location:449 → 479
      acid_disulf_rpt; acidic double-disulfide repeat

    38. XM_017312778.2 → XP_017168267.1  teneurin-3 isoform X15

      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      Conserved Domains (9) summary
      COG3209
      Location:1654 → 2165
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:919 → 958
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1574 → 1614
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:2069 → 2143
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:890 → 1249
      NHL; NHL repeat unit of beta-propeller proteins
      pfam05593
      Location:1366 → 1397
      RHS_repeat; RHS Repeat
      pfam06484
      Location:1 → 36
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2366 → 2443
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:194 → 536
      exchanger_TraA; outer membrane exchange protein TraA

    39. XM_036154008.1 → XP_036009901.1  teneurin-3 isoform X15

      UniProtKB/Swiss-Prot
      A0A2K9QKY6, A0A2K9QKZ0, A0A2K9QL01, A0A2K9QL03, A0A2K9QL04, A0A2K9QL11, A0A2K9QL36, A0A2K9QL87, Q3UVR9, Q3UX72, Q80TD2, Q8BSL5, Q9CSV2, Q9JLC1, Q9WTS6
      Conserved Domains (9) summary
      COG3209
      Location:1654 → 2165
      RhsA; Uncharacterized conserved protein RhsA, contains 28 RHS repeats [General function prediction only]
      cd05819
      Location:919 → 958
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1574 → 1614
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:2069 → 2143
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:890 → 1249
      NHL; NHL repeat unit of beta-propeller proteins
      pfam05593
      Location:1366 → 1397
      RHS_repeat; RHS Repeat
      pfam06484
      Location:1 → 36
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:2366 → 2443
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin
      NF033759
      Location:194 → 536
      exchanger_TraA; outer membrane exchange protein TraA

    40. XM_030243527.2 → XP_030099387.1  teneurin-3 isoform X22

      Conserved Domains (9) summary
      COG3209
      Location:1304 → 1794
      RhsA; Uncharacterized conserved protein RhaS, contains 28 RHS repeats [General function prediction only]
      cd00054
      Location:117 → 146
      EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
      cd05819
      Location:548 → 587
      NHL; NHL repeat [structural motif]
      TIGR01643
      Location:1203 → 1243
      YD_repeat_2x; YD repeat (two copies)
      TIGR03696
      Location:1698 → 1772
      Rhs_assc_core; RHS repeat-associated core domain
      cl18310
      Location:519 → 878
      NHL; NHL repeat unit of beta-propeller proteins
      pfam05593
      Location:995 → 1028
      RHS_repeat; RHS Repeat
      pfam06484
      Location:1 → 36
      Ten_N; Teneurin Intracellular Region
      pfam15636
      Location:1995 → 2072
      Tox-GHH; GHH signature containing HNH/Endo VII superfamily nuclease toxin

    41. XM_036154014.1 → XP_036009907.1  teneurin-3 isoform X25

      Conserved Domains (6) summary
      cd05819
      Location:1227 → 1266
      NHL; NHL repeat [structural motif]
      cl18310
      Location:1198 → 1557
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:192 → 351
      Ten_N; Teneurin Intracellular Region
      NF033662
      Location:828 → 858
      acid_disulf_rpt; acidic double-disulfide repeat
      NF033759
      Location:559 → 821
      exchanger_TraA; outer membrane exchange protein TraA
      cl19567
      Location:740 → 781
      DSL; Delta serrate ligand

    42. XM_036154013.1 → XP_036009906.1  teneurin-3 isoform X24

      Conserved Domains (6) summary
      cd05819
      Location:1234 → 1273
      NHL; NHL repeat [structural motif]
      cl18310
      Location:1205 → 1564
      NHL; NHL repeat unit of beta-propeller proteins
      pfam06484
      Location:192 → 351
      Ten_N; Teneurin Intracellular Region
      NF033662
      Location:835 → 865
      acid_disulf_rpt; acidic double-disulfide repeat
      NF033759
      Location:565 → 765
      exchanger_TraA; outer membrane exchange protein TraA
      cl19567
      Location:740 → 781
      DSL; Delta serrate ligand
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9WTS6.1 GenPept UniProtKB/Swiss-Prot:Q9WTS6

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