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    Reep4 receptor accessory protein 4 [ Mus musculus (house mouse) ]

    Gene ID: 72549, updated on 9-Dec-2024

    Summary

    Official Symbol
    Reep4provided by MGI
    Official Full Name
    receptor accessory protein 4provided by MGI
    Primary source
    MGI:MGI:1919799
    See related
    Ensembl:ENSMUSG00000033589 AllianceGenome:MGI:1919799
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2700029E10Rik
    Summary
    Predicted to enable microtubule binding activity. Predicted to be involved in endoplasmic reticulum tubular network organization and mitotic nuclear membrane reassembly. Predicted to be located in endoplasmic reticulum. Predicted to be active in cytoplasmic microtubule; endoplasmic reticulum membrane; and endoplasmic reticulum tubular network. Is expressed in vibrissa. Orthologous to human REEP4 (receptor accessory protein 4). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in testis adult (RPKM 61.3), thymus adult (RPKM 48.5) and 25 other tissues See more
    Orthologs
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    Genomic context

    See Reep4 in Genome Data Viewer
    Location:
    14 D2; 14 36.32 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (70782666..70786375)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (70545223..70548935)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene surfactant associated protein C Neighboring gene leucine-rich repeat LGI family, member 3 Neighboring gene STARR-positive B cell enhancer ABC_E7333 Neighboring gene STARR-positive B cell enhancer ABC_E1901 Neighboring gene lysine demethylase and nuclear receptor corepressor Neighboring gene predicted gene, 53866

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables microtubule binding  
    enables microtubule binding  
    Process Evidence Code Pubs
    involved_in cell division  
    involved_in endoplasmic reticulum tubular network organization  
    involved_in mitotic nuclear membrane reassembly  
    involved_in mitotic nuclear membrane reassembly  
    involved_in nuclear envelope organization  
    involved_in nuclear envelope organization  
    Component Evidence Code Pubs
    is_active_in cytoplasmic microtubule  
    located_in endoplasmic reticulum  
    located_in endoplasmic reticulum  
    is_active_in endoplasmic reticulum membrane  
    located_in endoplasmic reticulum membrane  
    is_active_in endoplasmic reticulum tubular network  
    located_in microtubule  

    General protein information

    Preferred Names
    receptor expression-enhancing protein 4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_180588.2NP_850919.1  receptor expression-enhancing protein 4

      See identical proteins and their annotated locations for NP_850919.1

      Status: VALIDATED

      Source sequence(s)
      AC122268, BC033929, BF464286
      Consensus CDS
      CCDS27256.1
      UniProtKB/Swiss-Prot
      Q8K072
      Related
      ENSMUSP00000040162.4, ENSMUST00000047218.5
      Conserved Domains (2) summary
      PRK11675
      Location:211243
      PRK11675; LexA regulated protein; Provisional
      pfam03134
      Location:794
      TB2_DP1_HVA22; TB2/DP1, HVA22 family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      70782666..70786375
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006519598.5XP_006519661.1  receptor expression-enhancing protein 4 isoform X1

      UniProtKB/TrEMBL
      A0A2I3BQJ3
      Related
      ENSMUSP00000154206.2, ENSMUST00000226563.2
      Conserved Domains (2) summary
      PRK11675
      Location:247279
      PRK11675; LexA regulated protein; Provisional
      pfam03134
      Location:19130
      TB2_DP1_HVA22; TB2/DP1, HVA22 family
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