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    mae1 plasma membrane malate/succinate:proton symporter Mae1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2543334, updated on 14-Nov-2024

    Summary

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    Official Symbol
    mae1
    Official Full Name
    plasma membrane malate/succinate:proton symporter Mae1
    Primary source
    PomBase:SPAPB8E5.03
    Locus tag
    SPOM_SPAPB8E5.03
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See mae1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    1
    Sequence:
    Chromosome: I; NC_003424.3 (4912249..4914182)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene 19S proteasome regulatory subunit Rpn502 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene phosphatidylglycerol/phosphatidylinositol transfer protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Cytotoxic thio-malate is transported by both an aluminum-responsive malate efflux pathway in wheat and the MAE1 malate permease in Schizosaccharomyces pombe. Osawa H, et al. Planta, 2006 Jul. PMID 16450171
    2. Characterization of Schizosaccharomyces pombe malate permease by expression in Saccharomyces cerevisiae. Camarasa C, et al. Appl Environ Microbiol, 2001 Sep. PMID 11526017, Free PMC Article
    3. The mae1 gene of Schizosaccharomyces pombe encodes a permease for malate and other C4 dicarboxylic acids. Grobler J, et al. Yeast, 1995 Dec. PMID 8750236
    4. Transport of malic acid in the yeast Schizosaccharomyces pombe: evidence for a proton-dicarboxylate symport. Sousa MJ, et al. Yeast, 1992 Dec. PMID 1293882
    5. Malic acid production by Saccharomyces cerevisiae: engineering of pyruvate carboxylation, oxaloacetate reduction, and malate export. Zelle RM, et al. Appl Environ Microbiol, 2008 May. PMID 18344340, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables malate transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables malate:proton symporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables malate:proton symporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables malonate(1-) transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables succinate transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables succinate:proton symporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in malate import across plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in malate import across plasma membrane IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in malonic acid import across plasma membrane IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in succinate import across plasma membrane IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in plasma membrane IC
    Inferred by Curator
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    plasma membrane malate/succinate:proton symporter Mae1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      4912249..4914182
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001020205.3 → NP_594777.1  plasma membrane malate/succinate:proton symporter Mae1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_594777.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      A1EGU0, P50537
      Conserved Domains (1) summary
      cd09317
      Location:38 → 369
      TDT_Mae1_like; C4-dicarboxylate transporter/malic acid transport protein family includes Mae1
    Nucleotide Protein
    Heading Accession and Version

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