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    rdp1 RNA-directed RNA polymerase (RDRC) Rdp1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2542198, updated on 18-Sep-2024

    Summary

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    Official Symbol
    rdp1
    Official Full Name
    RNA-directed RNA polymerase (RDRC) Rdp1
    Primary source
    PomBase:SPAC6F12.09
    Locus tag
    SPOM_SPAC6F12.09
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
    Also known as
    csp7; rdr1
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    Genomic context

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    See rdp1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    2
    Sequence:
    Chromosome: I; NC_003424.3 (1324941..1329061)

    Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene exocyst complex subunit Exo84 Neighboring gene ncRNA Neighboring gene phosphoribosylformylglycinamidine synthase Ade3 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene transcription factor TFIIIC subunit Sfc1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003424.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Hairpin RNA induces secondary small interfering RNA synthesis and silencing in trans in fission yeast. Simmer F, et al. EMBO Rep, 2010 Feb. PMID 20062003, Free PMC Article
    2. The karyopherin Sal3 is required for nuclear import of the core RNA interference pathway protein Rdp1. Park J, et al. Traffic, 2012 Apr. PMID 22268381
    3. Dicer associates with chromatin to repress genome activity in Schizosaccharomyces pombe. Woolcock KJ, et al. Nat Struct Mol Biol, 2011 Jan. PMID 21151114
    4. Regulation of heterochromatic silencing and histone H3 lysine-9 methylation by RNAi. Volpe TA, et al. Science, 2002 Sep 13. PMID 12193640
    5. The Kinesin motor protein Cut7 regulates biogenesis and function of Ago1-complexes. Stoica C, et al. Traffic, 2010 Jan. PMID 19883398

    See all (37) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Studies indicate that S. pombe genome encodes one of each of the core RNAi proteins, Dicer, Argonaute and RNA-dependent RNA polymerase (dcr1, ago1, rdp1).
      Title: RNAi mediates post-transcriptional repression of gene expression in fission yeast Schizosaccharomyces pombe.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables RNA-dependent RNA polymerase activity EXP
    Inferred from Experiment
    more info
    		 PubMed 
    enables RNA-dependent RNA polymerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA-dependent RNA polymerase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables RNA-dependent RNA polymerase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in co-transcriptional gene silencing by RNA interference machinery IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of G0 to G1 transition IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in regulatory ncRNA-mediated heterochromatin formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in siRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in siRNA-mediated pericentric heterochromatin formation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in siRNA-mediated pericentric heterochromatin formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in silent mating-type cassette heterochromatin formation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in chromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in chromosome, subtelomeric region IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in chromosome, telomeric repeat region IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in mating-type region heterochromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of nuclear RNA-directed RNA polymerase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of nuclear RNA-directed RNA polymerase complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in pericentric heterochromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in subtelomeric heterochromatin IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    RNA-directed RNA polymerase (RDRC) Rdp1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003424.3 Reference assembly

      Range
      1324941..1329061
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001356008.2 → NP_001342838.1  RNA-directed RNA polymerase (RDRC) Rdp1 [Schizosaccharomyces pombe]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      O14227
      Conserved Domains (1) summary
      pfam05183
      Location:461 → 1037
      RdRP; RNA dependent RNA polymerase
    Nucleotide Protein
    Heading Accession and Version

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