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    git1 C2 domain protein Git1 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540617, updated on 18-Sep-2024

    Summary

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    Official Symbol
    git1
    Official Full Name
    C2 domain protein Git1
    Primary source
    PomBase:SPBC21C3.20c
    Locus tag
    SPOM_SPBC21C3.20C
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See git1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (3831185..3834990, complement)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene SBDS family protein Rtc3 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene splicing factor Cxr1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Schizosaccharomyces pombe Git1 is a C2-domain protein required for glucose activation of adenylate cyclase. Kao RS, et al. Genetics, 2006 May. PMID 16489217, Free PMC Article
    2. Glucose repression of fbp1 transcription of Schizosaccharomyces pombe is partially regulated by adenylate cyclase activation by a G protein alpha subunit encoded by gpa2 (git8). Nocero M, et al. Genetics, 1994 Sep. PMID 8001792, Free PMC Article
    3. Six git genes encode a glucose-induced adenylate cyclase activation pathway in the fission yeast Schizosaccharomyces pombe. Byrne SM, et al. J Cell Sci, 1993 Aug. PMID 8227198, Free PMC Article
    4. The cAMP signaling pathway regulates Epe1 protein levels and heterochromatin assembly. Bao K, et al. PLoS Genet, 2022 Feb. PMID 35171902, Free PMC Article
    5. Glucose repression of transcription of the Schizosaccharomyces pombe fbp1 gene occurs by a cAMP signaling pathway. Hoffman CS, et al. Genes Dev, 1991 Apr. PMID 1849107

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Git1 is a critical component of the S. pombe glucose/cAMP pathway.
      Title: Schizosaccharomyces pombe Git1 is a C2-domain protein required for glucose activation of adenylate cyclase.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in adenylate cyclase-activating glucose-activated G protein-coupled receptor signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in negative regulation of induction of conjugation with cellular fusion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cell division site HDA PubMed 
    is_active_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in mitotic spindle pole body HDA PubMed 
    is_active_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    C2 domain protein Git1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      3831185..3834990 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001022520.3 → NP_596600.1  C2 domain protein Git1 [Schizosaccharomyces pombe]

      See identical proteins and their annotated locations for NP_596600.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9P7K5
      Conserved Domains (1) summary
      cl14603
      Location:806 → 900
      C2; C2 domain
    Nucleotide Protein
    Heading Accession and Version

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