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    alp4 gamma tubulin complex GCP2 subunit Alp4 [ Schizosaccharomyces pombe (fission yeast) ]

    Gene ID: 2540392, updated on 18-Sep-2024

    Summary

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    Official Symbol
    alp4
    Official Full Name
    gamma tubulin complex GCP2 subunit Alp4
    Primary source
    PomBase:SPBC365.15
    Locus tag
    SPOM_SPBC365.15
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Schizosaccharomyces pombe (strain: 972h-)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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    Genomic context

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    See alp4 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003423.3 (2524061..2527134)

    Chromosome II - NC_003423.3Genomic Context describing neighboring genes Neighboring gene UDP-glucose 4-epimerase Uge1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003423.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The carboxy-terminus of Alp4 alters microtubule dynamics to induce oscillatory nuclear movement led by the spindle pole body in Schizosaccharomyces pombe. Masuda H, et al. Genes Cells, 2006 Apr. PMID 16611238
    2. Effects of {gamma}-tubulin complex proteins on microtubule nucleation and catastrophe in fission yeast. Zimmerman S, et al. Mol Biol Cell, 2005 Jun. PMID 15772152, Free PMC Article
    3. Gamma-tubulin complex-mediated anchoring of spindle microtubules to spindle-pole bodies requires Msd1 in fission yeast. Toya M, et al. Nat Cell Biol, 2007 Jun. PMID 17486116
    4. Efficient formation of bipolar microtubule bundles requires microtubule-bound gamma-tubulin complexes. Janson ME, et al. J Cell Biol, 2005 Apr 25. PMID 15837798, Free PMC Article
    5. Hrs1p/Mcp6p on the meiotic SPB organizes astral microtubule arrays for oscillatory nuclear movement. Tanaka K, et al. Curr Biol, 2005 Aug 23. PMID 16111942

    See all (42) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by PomBase

    Function Evidence Code Pubs
    enables gamma-tubulin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    contributes_to microtubule minus-end binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    contributes_to microtubule nucleator activity TAS
    Traceable Author Statement
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in astral microtubule anchoring at mitotic spindle pole body IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in cytoplasmic microtubule organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in cytoplasmic microtubule organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in meiotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in microtubule nucleation IC
    Inferred by Curator
    more info
    		 PubMed 
    involved_in mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in mitotic spindle assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in nuclear migration by microtubule mediated pushing forces IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in spindle assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cell division site HDA PubMed 
    is_active_in cytosol HDA PubMed 
    is_active_in equatorial microtubule organizing center IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of gamma-tubulin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of gamma-tubulin ring complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of gamma-tubulin small complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in half bridge of mitotic spindle pole body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in inner plaque of mitotic spindle pole body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in interphase microtubule organizing center IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in meiotic spindle pole body EXP
    Inferred from Experiment
    more info
    		 PubMed 
    is_active_in meiotic spindle pole body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in mitotic spindle pole body HDA PubMed 
    is_active_in mitotic spindle pole body IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in mitotic spindle pole body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus HDA PubMed 
    is_active_in old mitotic spindle pole body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    gamma tubulin complex GCP2 subunit Alp4

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003423.3 Reference assembly

      Range
      2524061..2527134
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001021954.3 → NP_596044.1  gamma tubulin complex GCP2 subunit Alp4 [Schizosaccharomyces pombe]

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      Q9Y705
      Conserved Domains (1) summary
      pfam04130
      Location:74 → 693
      Spc97_Spc98; Spc97 / Spc98 family
    Nucleotide Protein
    Heading Accession and Version

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