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    ZK970.8 Mss4 protein [ Caenorhabditis elegans ]

    Gene ID: 3565809, updated on 4-Jan-2025

    Summary

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    Official Symbol
    ZK970.8
    Official Full Name
    Mss4 protein
    Primary source
    WormBase:WBGene00014174
    Locus tag
    CELE_ZK970.8
    See related
    AllianceGenome:WB:WBGene00014174
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable guanyl-nucleotide exchange factor activity and zinc ion binding activity. Predicted to be involved in post-Golgi vesicle-mediated transport. Predicted to be active in cytosol and membrane. Orthologous to human RABIF (RAB interacting factor). [provided by Alliance of Genome Resources, Jan 2025]
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    Genomic context

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    See ZK970.8 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    1
    Sequence:
    Chromosome: II; NC_003280.10 (10309637..10310068)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Receptor-type guanylate cyclase gcy-4 Neighboring gene tRNA-Pro Neighboring gene ncRNA Neighboring gene Receptor-type guanylate cyclase gcy-5 Neighboring gene SXP/RAL-2 family protein Ani s 5-like cation-binding domain-containing protein Neighboring gene Activated in Blocked Unfolded protein response Neighboring gene Lipoprotein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables guanyl-nucleotide exchange factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables guanyl-nucleotide exchange factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in post-Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in small GTPase-mediated signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Mss4 protein
    NP_001367069.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      10309637..10310068
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001381577.1 → NP_001367069.1  Mss4 protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7YWN1
      Conserved Domains (1) summary
      cl00180
      Location:50 → 140
      RabGEF; Nucleotide exchange factor for Rab-like small GTPases (RabGEF), Mss4 type; RabGEF positely regulates the function of Rab GTPase by promoting exchange of GDP for GTP; members of the Rab subfamily of Ras GTPases are important in vesicular transport;
    Nucleotide Protein
    Heading Accession and Version

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