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    Insulinase (Peptidase family M16) protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841627, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Insulinase (Peptidase family M16) protein
    Primary source
    TAIR:AT1G51980
    Locus tag
    AT1G51980
    See related
    Araport:AT1G51980
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F5F19.4; F5F19_4
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    13
    Sequence:
    Chromosome: 1; NC_003070.9 (19323055..19326918, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene IQ-domain 27 Neighboring gene ABA Overly-Sensitive 5 Neighboring gene B3 domain protein Neighboring gene O-methyltransferase family protein Neighboring gene Mannose-binding lectin superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Arabidopsis PPR40 connects abiotic stress responses to mitochondrial electron transport. Zsigmond L, et al. Plant Physiol, 2008 Apr. PMID 18305213, Free PMC Article
    2. A transcriptomic and proteomic characterization of the Arabidopsis mitochondrial protein import apparatus and its response to mitochondrial dysfunction. Lister R, et al. Plant Physiol, 2004 Feb. PMID 14730085, Free PMC Article
    3. Analysis of the soluble ATP-binding proteome of plant mitochondria identifies new proteins and nucleotide triphosphate interactions within the matrix. Ito J, et al. J Proteome Res, 2006 Dec. PMID 17137349
    4. Resolving and identifying protein components of plant mitochondrial respiratory complexes using three dimensions of gel electrophoresis. Meyer EH, et al. J Proteome Res, 2008 Feb. PMID 18189341
    5. Analysis of the Arabidopsis mitochondrial proteome. Millar AH, et al. Plant Physiol, 2001 Dec. PMID 11743115, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001084232.1
    NM_104079.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP binding HDA PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metalloendopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus HDA PubMed 
    located_in plant-type vacuole HDA PubMed 
    part_of respiratory chain complex III HDA PubMed 

    General protein information

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    Preferred Names
    Insulinase (Peptidase family M16) protein
    NP_001077701.1
    • Insulinase (Peptidase family M16) protein; FUNCTIONS IN: metalloendopeptidase activity, ATP binding; INVOLVED IN: proteolysis, response to salt stress; LOCATED IN: mitochondrion, plasma membrane, plastid, mitochondrial respiratory chain complex III, membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase M16, zinc-binding site (InterPro:IPR001431), Peptidase M16, C-terminal (InterPro:IPR007863), Peptidase M16, N-terminal (InterPro:IPR011765), Metalloenzyme, LuxS/M16 peptidase-like, metal-binding (InterPro:IPR011249), Peptidase M16, core (InterPro:IPR011237); BEST Arabidopsis thaliana protein match is: mitochondrial processing peptidase alpha subunit (TAIR:AT3G16480.1); Has 5945 Blast hits to 5839 proteins in 1469 species: Archae - 10; Bacteria - 3395; Metazoa - 673; Fungi - 538; Plants - 242; Viruses - 3; Other Eukaryotes - 1084 (source: NCBI BLink).
    NP_175610.1
    • Insulinase (Peptidase family M16) protein; FUNCTIONS IN: metalloendopeptidase activity, ATP binding; INVOLVED IN: proteolysis, response to salt stress; LOCATED IN: in 6 components; EXPRESSED IN: 28 plant structures; EXPRESSED DURING: 16 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase M16, zinc-binding site (InterPro:IPR001431), Peptidase M16, C-terminal (InterPro:IPR007863), Peptidase M16, N-terminal (InterPro:IPR011765), Metalloenzyme, LuxS/M16 peptidase-like, metal-binding (InterPro:IPR011249), Peptidase M16, core (InterPro:IPR011237); BEST Arabidopsis thaliana protein match is: mitochondrial processing peptidase alpha subunit (TAIR:AT3G16480.1); Has 6114 Blast hits to 5997 proteins in 1482 species: Archae - 10; Bacteria - 3458; Metazoa - 684; Fungi - 568; Plants - 250; Viruses - 3; Other Eukaryotes - 1141 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      19323055..19326918 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_104079.4 → NP_175610.1  Insulinase (Peptidase family M16) protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_175610.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0WW81, Q8L9K3, Q9ZU25
      UniProtKB/TrEMBL
      A0A178W8B9, A0A5S9WL25, A0A654ETF0
      Conserved Domains (1) summary
      COG0612
      Location:58 → 480
      PqqL; Predicted Zn-dependent peptidase [General function prediction only]

    2. NM_001084232.1 → NP_001077701.1  Insulinase (Peptidase family M16) protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001077701.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654ETF0, A8MQE5
      Conserved Domains (3) summary
      COG0612
      Location:58 → 451
      PqqL; Predicted Zn-dependent peptidase [General function prediction only]
      pfam00675
      Location:88 → 234
      Peptidase_M16; Insulinase (Peptidase family M16)
      pfam05193
      Location:239 → 422
      Peptidase_M16_C; Peptidase M16 inactive domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZU25.1

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