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    SAR2 secretion-associated RAS super family 2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 827368, updated on 18-Sep-2024

    Summary

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    Official Symbol
    SAR2
    Official Full Name
    secretion-associated RAS super family 2
    Primary source
    TAIR:AT4G02080
    Locus tag
    AT4G02080
    See related
    Araport:AT4G02080
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ASAR1; ATSAR2; ATSARA1C; secretion-associated RAS super family 2; T10M13.9; T10M13_9
    Summary
    A member of ARF-like GTPase family. A thaliana has 21 members, in two subfamilies, ARF and ARF-like (ARL) GTPases.
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    Genomic context

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    See SAR2 in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    3
    Sequence:
    Chromosome: 4; NC_003075.7 (921447..922759)

    Chromosome 4 - NC_003075.7Genomic Context describing neighboring genes Neighboring gene MUTS homolog 6 Neighboring gene RING/FYVE/PHD zinc finger superfamily protein Neighboring gene multidrug resistance protein ABC transporter family protein Neighboring gene Heat shock protein DnaJ with tetratricopeptide repeat-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003075.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Unique COPII component AtSar1a/AtSec23a pair is required for the distinct function of protein ER export in Arabidopsis thaliana. Zeng Y, et al. Proc Natl Acad Sci U S A, 2015 Nov 17. PMID 26578783, Free PMC Article
    2. COPII Components Sar1b and Sar1c Play Distinct Yet Interchangeable Roles in Pollen Development. Liang X, et al. Plant Physiol, 2020 Jul. PMID 32327549, Free PMC Article
    3. Arabidopsis OBG-like GTPase (AtOBGL) is localized in chloroplasts and has an essential function in embryo development. Chigri F, et al. Mol Plant, 2009 Nov. PMID 19995735
    4. Analysis of the small GTPase gene superfamily of Arabidopsis. Vernoud V, et al. Plant Physiol, 2003 Mar. PMID 12644670, Free PMC Article
    5. Identification of new intrinsic proteins in Arabidopsis plasma membrane proteome. Marmagne A, et al. Mol Cell Proteomics, 2004 Jul. PMID 15060130

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Unique COPII component AtSar1a/AtSec23a pair is required for the distinct function of protein ER export in Arabidopsis thaliana.
      Title: Unique COPII component AtSar1a/AtSec23a pair is required for the distinct function of protein ER export in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_116440.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables GTP binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within pollen development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Component Evidence Code Pubs
    NOT located_in cytosol RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in plasma membrane HDA PubMed 

    General protein information

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    Preferred Names
    secretion-associated RAS super family 2
    NP_192117.1
    • secretion-associated RAS super family 2 (SAR2); FUNCTIONS IN: GTP binding; INVOLVED IN: intracellular protein transport; LOCATED IN: plasma membrane; EXPRESSED IN: 26 plant structures; EXPRESSED DURING: 15 growth stages; CONTAINS InterPro DOMAIN/s: Small GTP-binding protein (InterPro:IPR005225), Small GTPase SAR1-type (InterPro:IPR006687), ARF/SAR superfamily (InterPro:IPR006689); BEST Arabidopsis thaliana protein match is: Ras-related small GTP-binding family protein (TAIR:AT3G62560.1); Has 6784 Blast hits to 6782 proteins in 374 species: Archae - 2; Bacteria - 40; Metazoa - 3245; Fungi - 1245; Plants - 1081; Viruses - 0; Other Eukaryotes - 1171 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003075.7 Reference assembly

      Range
      921447..922759
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_116440.4 → NP_192117.1  secretion-associated RAS super family 2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_192117.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O04747, O04748, O04834, O04835, Q42142, Q96296
      UniProtKB/TrEMBL
      A0A178V5S8, A0A5S9XPU9
      Conserved Domains (1) summary
      cd00879
      Location:2 → 192
      Sar1; Sar1 is an essential component of COPII vesicle coats
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O04834.1

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