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    prr12a proline rich 12a [ Danio rerio (zebrafish) ]

    Gene ID: 564766, updated on 9-Dec-2024

    Summary

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    Official Symbol
    prr12aprovided by ZNC
    Official Full Name
    proline rich 12aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041111-223
    See related
    Ensembl:ENSDARG00000074229 AllianceGenome:ZFIN:ZDB-GENE-041111-223
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fj88e10; im:7144812; wu:fj88e10; si:dkey-94f20.3
    Summary
    Orthologous to human PRR12 (proline rich 12). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See prr12a in Genome Data Viewer
    Location:
    chromosome: 12
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 12 NC_007123.7 (4601349..4632194, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 12 NC_007123.6 (4566321..4597287, complement)

    Chromosome 12 - NC_007123.7Genomic Context describing neighboring genes Neighboring gene si:dkey-94f20.4 Neighboring gene interferon regulatory factor 3 Neighboring gene BR serine/threonine kinase 1a Neighboring gene si:ch211-255p10.3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Shedding a Light on Dark Genes: A Comparative Expression Study of PRR12 Orthologues during Zebrafish Development. Muscò A, et al. Genes (Basel), 2024 Apr 15. PMID 38674426, Free PMC Article
    2. A network of epigenetic regulators guides developmental haematopoiesis in vivo. Huang HT, et al. Nat Cell Biol, 2013 Dec. PMID 24240475, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Shedding a Light on Dark Genes: A Comparative Expression Study of PRR12 Orthologues during Zebrafish Development.
      Title: Shedding a Light on Dark Genes: A Comparative Expression Study of PRR12 Orthologues during Zebrafish Development.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    proline rich 12a; proline-rich protein 12
    Names
    filaggrin-2
    zmp:0000000744

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007123.7 Reference GRCz11 Primary Assembly

      Range
      4601349..4632194 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005156015.5 → XP_005156072.1  proline-rich protein 12 isoform X2

      UniProtKB/TrEMBL
      A0A8M2B2M9
      Conserved Domains (1) summary
      pfam13926
      Location:2350 → 2450
      DUF4211; Domain of unknown function (DUF4211)

    2. XM_005156014.5 → XP_005156071.1  proline-rich protein 12 isoform X1

      UniProtKB/TrEMBL
      A0A0R4IRJ4, A0A8M2B2W6
      Related
      ENSDARP00000137218.1, ENSDART00000110514.6
      Conserved Domains (1) summary
      pfam13926
      Location:2351 → 2451
      DUF4211; Domain of unknown function (DUF4211)
    Nucleotide Protein Strain
    Heading Accession and Version

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    Research Materials