plrdgb PITP-less RdgB-like protein [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: plrdgbprovided by ZNC
Official Full Name: PITP-less RdgB-like proteinprovided by ZNC
Primary source: ZFIN:ZDB-GENE-000406-3
See related: Ensembl:ENSDARG00000089101 AllianceGenome:ZFIN:ZDB-GENE-000406-3
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: si:ch1073-443k13.2
Summary: Predicted to enable metal ion binding activity and phospholipid transporter activity. Predicted to act upstream of or within phospholipid transport. Human ortholog(s) of this gene implicated in cone-rod dystrophy 5. Orthologous to human PITPNM3 (PITPNM family member 3). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 21

Exon count:: 21

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	21	NC_007132.7 (39693331..39898680)
105	previous assembly	GRCz10 (GCF_000002035.5)	21	NC_007132.6 (39681932..39863981)

Chromosome 21 - NC_007132.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables phospholipid transporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within phospholipid transport	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: PITP-less RdgB-like protein

Names: zmp:0000000523

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_131575.2 → NP_571650.2 PITP-less RdgB-like protein

Status: VALIDATED

Source sequence(s)

CABZ01065288, CABZ01065289, CABZ01080796, CABZ01080799, CU694476, CU694954, CU855550, FO722024

UniProtKB/TrEMBL

Q9I9N8

Related

ENSDARP00000135456.2, ENSDART00000168996.2

Conserved Domains (3) summary

smart00775
Location:697 → 828

LNS2; This domain is found in Saccharomyces cerevisiae protein SMP2, proteins with an N-terminal lipin domain and phosphatidylinositol transfer proteins

COG5083
Location:553 → 844

SMP2; Phosphatidate phosphatase PAH1, contains Lipin and LNS2 domains. can be involved in plasmid maintenance [Lipid transport and metabolism]

pfam02862
Location:363 → 551

DDHD; DDHD domain