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    ahr2 aryl hydrocarbon receptor 2 [ Danio rerio (zebrafish) ]

    Gene ID: 30517, updated on 9-Dec-2024

    Summary

    Official Symbol
    ahr2provided by ZNC
    Official Full Name
    aryl hydrocarbon receptor 2provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-990714-16
    See related
    Ensembl:ENSDARG00000021833 AllianceGenome:ZFIN:ZDB-GENE-990714-16
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    ahrb
    Summary
    Enables nuclear receptor activity and sequence-specific DNA binding activity. Contributes to DNA binding activity. Acts upstream of or within several processes, including fin development; ovarian follicle development; and positive regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Is expressed in several structures, including blood vessel; fin; mandibular arch skeleton; nervous system; and pleuroperitoneal region. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See ahr2 in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 22 NC_007133.7 (13046270..13164730, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 22 NC_007133.6 (13021493..13139953, complement)

    Chromosome 22 - NC_007133.7Genomic Context describing neighboring genes Neighboring gene leucine-rich repeat-containing protein 15 Neighboring gene aryl hydrocarbon receptor 1b Neighboring gene contactin associated protein family member 5b Neighboring gene uncharacterized LOC137488915

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    General gene information

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to organic cyclic compound PubMed 
    acts_upstream_of_or_within cellular response to organic cyclic compound PubMed 
    acts_upstream_of_or_within cellular response to xenobiotic stimulus PubMed 
    acts_upstream_of_or_within cellular response to xenobiotic stimulus PubMed 
    acts_upstream_of_or_within cranial skeletal system development PubMed 
    acts_upstream_of_or_within fin development PubMed 
    involved_in intracellular receptor signaling pathway  
    acts_upstream_of_or_within multicellular organismal reproductive process PubMed 
    acts_upstream_of_or_within ovarian follicle development PubMed 
    acts_upstream_of_or_within positive regulation of DNA-templated transcription PubMed 
    acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II PubMed 
    acts_upstream_of_or_within regulation of DNA-templated transcription  
    involved_in regulation of transcription by RNA polymerase II  
    acts_upstream_of_or_within regulation of transcription by RNA polymerase II PubMed 
    acts_upstream_of_or_within response to toxic substance PubMed 
    acts_upstream_of_or_within response to xenobiotic stimulus PubMed 
    acts_upstream_of_or_within response to xenobiotic stimulus  
    acts_upstream_of_or_within response to xenobiotic stimulus PubMed 
    acts_upstream_of_or_within response to xenobiotic stimulus PubMed 
    acts_upstream_of_or_within rhythmic process  
    acts_upstream_of_or_within xenobiotic metabolic process  
    Component Evidence Code Pubs
    part_of aryl hydrocarbon receptor complex  
    located_in cytoplasm PubMed 
    is_active_in nucleus  
    located_in nucleus PubMed 

    General protein information

    Preferred Names
    aryl hydrocarbon receptor 2
    Names
    AHR1b
    aryl hydrocarbon receptor b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_131264.1 → NP_571339.1  aryl hydrocarbon receptor 2

      See identical proteins and their annotated locations for NP_571339.1

      Status: PROVISIONAL

      Source sequence(s)
      AF063446
      UniProtKB/TrEMBL
      Q9YGV3
      Related
      ENSDARP00000096540.3, ENSDART00000105762.4
      Conserved Domains (5) summary
      smart00091
      Location:120 → 183
      PAS; PAS domain
      cd00083
      Location:35 → 76
      HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
      cd00130
      Location:305 → 385
      PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
      pfam00989
      Location:118 → 232
      PAS; PAS fold
      pfam14598
      Location:292 → 396
      PAS_11; PAS domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007133.7 Reference GRCz11 Primary Assembly

      Range
      13046270..13164730 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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