mibp2 muscle-specific beta 1 integrin binding protein 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: mibp2provided by ZNC
Official Full Name: muscle-specific beta 1 integrin binding protein 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-031113-14
See related: Ensembl:ENSDARG00000101844 AllianceGenome:ZFIN:ZDB-GENE-031113-14
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: cb985
Summary: Predicted to enable ribosylnicotinamide kinase activity. Acts upstream of or within basement membrane assembly; cell-substrate junction assembly; and muscle organ development. Predicted to be active in cytoplasm. Is expressed in several structures, including alar plate midbrain region; digestive system; immature eye; musculature system; and nervous system. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 18

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	18	NC_007129.7 (5490458..5496014)
105	previous assembly	GRCz10 (GCF_000002035.5)	18	NC_007129.6 (5637596..5643152)

Chromosome 18 - NC_007129.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ribosylnicotinamide kinase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within basement membrane assembly	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within cell-substrate junction assembly	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within integrin-mediated signaling pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within muscle organ development	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: muscle-specific beta 1 integrin binding protein 2

Names: nrk2b

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_198877.1 → NP_942578.1 muscle-specific beta 1 integrin binding protein 2

See identical proteins and their annotated locations for NP_942578.1

Status: PROVISIONAL

Source sequence(s)

BC047858

UniProtKB/TrEMBL

Q6NYH9, Q7ZUR6

Related

ENSDARP00000134727.1, ENSDART00000167035.3

Conserved Domains (1) summary

cd02024
Location:4 → 171

NRK1; Nicotinamide riboside kinase (NRK) is an enzyme involved in the metabolism of nicotinamide adenine dinucleotide (NAD+). This enzyme catalyzes the phosphorylation of nicotinamide riboside (NR) to form nicotinamide mononucleotide (NMN). It defines the NR ...