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    naa20 N-alpha-acetyltransferase 20, NatB catalytic subunit [ Danio rerio (zebrafish) ]

    Gene ID: 541516, updated on 9-Dec-2024

    Summary

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    Official Symbol
    naa20provided by ZNC
    Official Full Name
    N-alpha-acetyltransferase 20, NatB catalytic subunitprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050327-47
    See related
    Ensembl:ENSDARG00000039493 AllianceGenome:ZFIN:ZDB-GENE-050327-47
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    nat5; im:7150897; zgc:110819
    Summary
    Predicted to enable peptide alpha-N-acetyltransferase activity. Predicted to be involved in N-terminal protein amino acid acetylation and regulation of actin cytoskeleton organization. Predicted to be located in cytoplasm and nucleus. Predicted to be part of NatB complex. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 73. Orthologous to human NAA20 (N-alpha-acetyltransferase 20, NatB catalytic subunit). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See naa20 in Genome Data Viewer
    Location:
    chromosome: 20
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 20 NC_007131.7 (49105429..49117401, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 20 NC_007131.6 (49296011..49307983, complement)

    Chromosome 20 - NC_007131.7Genomic Context describing neighboring genes Neighboring gene cilia and flagella associated protein 61 Neighboring gene uncharacterized LOC137488702 Neighboring gene crooked neck pre-mRNA splicing factor 1 Neighboring gene uncharacterized LOC137488601 Neighboring gene CD109 molecule

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. The N-terminal acetyltransferase Naa10 is essential for zebrafish development. Ree R, et al. Biosci Rep, 2015 Aug 6. PMID 26251455, Free PMC Article
    2. The draft genome of the grass carp (Ctenopharyngodon idellus) provides insights into its evolution and vegetarian adaptation. Wang Y, et al. Nat Genet, 2015 Jun. PMID 25938946
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables acyltransferase activity, transferring groups other than amino-acyl groups IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables peptide alpha-N-acetyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in N-terminal peptidyl-aspartic acid acetylation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in N-terminal peptidyl-glutamic acid acetylation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in N-terminal peptidyl-glutamine acetylation ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in regulation of actin cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of NatB complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    N-alpha-acetyltransferase 20
    Names
    N-acetyltransferase 5
    N-terminal acetyltransferase B complex catalytic subunit NAA20
    N-terminal acetyltransferase B complex catalytic subunit NAT5
    methionine N-acetyltransferase
    natB catalytic subunit
    natB complex subunit NAT5
    NP_001014351.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001014329.2 → NP_001014351.1  N-alpha-acetyltransferase 20

      See identical proteins and their annotated locations for NP_001014351.1

      Status: PROVISIONAL

      Source sequence(s)
      BC091957
      UniProtKB/Swiss-Prot
      A2VD34, Q58ED9
      UniProtKB/TrEMBL
      B2GQZ5
      Related
      ENSDARP00000057699.5, ENSDART00000057700.6
      Conserved Domains (1) summary
      COG0456
      Location:1 → 156
      RimI; Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis]

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007131.7 Reference GRCz11 Primary Assembly

      Range
      49105429..49117401 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q58ED9.1 GenPept UniProtKB/Swiss-Prot:Q58ED9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.