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    alg8 ALG8 alpha-1,3-glucosyltransferase [ Danio rerio (zebrafish) ]

    Gene ID: 327601, updated on 9-Dec-2024

    Summary

    Official Symbol
    alg8provided by ZNC
    Official Full Name
    ALG8 alpha-1,3-glucosyltransferaseprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-5812
    See related
    Ensembl:ENSDARG00000044627 AllianceGenome:ZFIN:ZDB-GENE-030131-5812
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fi19e09; wu:fi19f07; zgc:112507; si:rp71-1p14.2
    Summary
    Predicted to enable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity. Predicted to be involved in dolichol-linked oligosaccharide biosynthetic process. Predicted to be located in endoplasmic reticulum. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation Ih and polycystic liver disease 3. Orthologous to human ALG8 (ALG8 alpha-1,3-glucosyltransferase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See alg8 in Genome Data Viewer
    Location:
    chromosome: 21
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 21 NC_007132.7 (22892836..22901407)
    105 previous assembly GRCz10 (GCF_000002035.5) 21 NC_007132.6 (22856231..22864802)

    Chromosome 21 - NC_007132.7Genomic Context describing neighboring genes Neighboring gene PCF11 cleavage and polyadenylation factor subunit Neighboring gene coiled-coil domain containing 90B Neighboring gene guanylate cyclase activator 1d Neighboring gene duboraya

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables glucosyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables hexosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in dolichol-linked oligosaccharide biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein N-linked glycosylation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within protein N-linked glycosylation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endoplasmic reticulum ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase
    Names
    asparagine-linked glycosylation 8 homolog (yeast, alpha-1,3-glucosyltransferase)
    NP_001017647.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001017647.1NP_001017647.1  dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase

      See identical proteins and their annotated locations for NP_001017647.1

      Status: PROVISIONAL

      Source sequence(s)
      BC093349
      UniProtKB/TrEMBL
      B2GQD0, F6NXK1, Q566T2
      Related
      ENSDARP00000065564.4, ENSDART00000065565.5
      Conserved Domains (1) summary
      pfam03155
      Location:20506
      Alg6_Alg8; ALG6, ALG8 glycosyltransferase family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007132.7 Reference GRCz11 Primary Assembly

      Range
      22892836..22901407
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018395091.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      317687..324632
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)