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    ssu72 SSU72 homolog, RNA polymerase II CTD phosphatase [ Danio rerio (zebrafish) ]

    Gene ID: 393701, updated on 9-Dec-2024

    Summary

    Official Symbol
    ssu72provided by ZNC
    Official Full Name
    SSU72 homolog, RNA polymerase II CTD phosphataseprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1689
    See related
    Ensembl:ENSDARG00000031216 AllianceGenome:ZFIN:ZDB-GENE-040426-1689
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:73143
    Summary
    Predicted to enable RNA polymerase II CTD heptapeptide repeat phosphatase activity. Predicted to be involved in termination of RNA polymerase II transcription. Predicted to act upstream of or within mRNA processing. Predicted to be located in cytoplasm and nucleus. Predicted to be part of mRNA cleavage and polyadenylation specificity factor complex. Is expressed in central nervous system. Orthologous to several human genes including SSU72 (SSU72 homolog, RNA polymerase II CTD phosphatase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See ssu72 in Genome Data Viewer
    Location:
    chromosome: 22
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 22 NC_007133.7 (359273..367569, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 22 NC_007133.6 (354626..362922, complement)

    Chromosome 22 - NC_007133.7Genomic Context describing neighboring genes Neighboring gene NECAP endocytosis associated 2 Neighboring gene transmembrane protein 240b Neighboring gene fibronectin type III domain containing 10 Neighboring gene olfactory receptor class A related 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Pathways from PubChem

    General gene information

    Clone Names

    • MGC73143

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA polymerase II CTD heptapeptide repeat phosphatase activity  
    enables hydrolase activity  
    enables myosin phosphatase activity  
    enables phosphoprotein phosphatase activity  
    enables protein serine/threonine phosphatase activity  
    Component Evidence Code Pubs
    located_in cytoplasm  
    part_of mRNA cleavage and polyadenylation specificity factor complex  
    located_in nucleus  

    General protein information

    Preferred Names
    RNA polymerase II subunit A C-terminal domain phosphatase SSU72
    Names
    CTD phosphatase SSU72
    SSU72 RNA polymerase II CTD phosphatase homolog
    NP_957022.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200728.1 → NP_957022.1  RNA polymerase II subunit A C-terminal domain phosphatase SSU72

      See identical proteins and their annotated locations for NP_957022.1

      Status: PROVISIONAL

      Source sequence(s)
      BC059504
      UniProtKB/Swiss-Prot
      Q6PC19
      Related
      ENSDARP00000041894.5, ENSDART00000041895.7
      Conserved Domains (1) summary
      pfam04722
      Location:6 → 194
      Ssu72; Ssu72-like protein

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007133.7 Reference GRCz11 Primary Assembly

      Range
      359273..367569 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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