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    slc25a19 solute carrier family 25 member 19 [ Danio rerio (zebrafish) ]

    Gene ID: 403024, updated on 9-Dec-2024

    Summary

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    Official Symbol
    slc25a19provided by ZNC
    Official Full Name
    solute carrier family 25 member 19provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050417-292
    See related
    Ensembl:ENSDARG00000100385 AllianceGenome:ZFIN:ZDB-GENE-050417-292
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:111878
    Summary
    Predicted to enable thiamine transmembrane transporter activity. Predicted to be involved in thiamine pyrophosphate transmembrane transport. Predicted to act upstream of or within transmembrane transport. Predicted to be located in membrane. Predicted to be active in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in inherited metabolic disorder and microcephaly. Orthologous to human SLC25A19 (solute carrier family 25 member 19). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See slc25a19 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (13487759..13509283, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (13337647..13363285, complement)

    Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene zgc:77748 Neighboring gene myeloid-associated differentiation marker Neighboring gene jumonji domain containing 8 Neighboring gene amidohydrolase domain containing 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Hematopoietic gene expression profile in zebrafish kidney marrow. Song HD, et al. Proc Natl Acad Sci U S A, 2004 Nov 16. PMID 15520368, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC111878

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables antiporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables thiamine pyrophosphate transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables thiamine transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in thiamine pyrophosphate transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrial inner membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    mitochondrial thiamine pyrophosphate carrier
    Names
    solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_205715.1 → NP_991278.1  mitochondrial thiamine pyrophosphate carrier

      See identical proteins and their annotated locations for NP_991278.1

      Status: PROVISIONAL

      Source sequence(s)
      AY394951
      UniProtKB/TrEMBL
      Q6TLF4
      Related
      ENSDARP00000130698.1, ENSDART00000166832.3
      Conserved Domains (2) summary
      PTZ00169
      Location:20 → 290
      PTZ00169; ADP/ATP transporter on adenylate translocase; Provisional
      pfam00153
      Location:117 → 203
      Mito_carr; Mitochondrial carrier protein

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007114.7 Reference GRCz11 Primary Assembly

      Range
      13487759..13509283 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

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