npy8br neuropeptide Y receptor Y8b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: npy8brprovided by ZNC
Official Full Name: neuropeptide Y receptor Y8bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-980526-208
See related: Ensembl:ENSDARG00000005780 AllianceGenome:ZFIN:ZDB-GENE-980526-208
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zyb; npyryb; zgc:194624; zgc:194648
Summary: Enables neuropeptide binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within signal transduction. Predicted to be located in membrane. Predicted to be active in neuron projection and plasma membrane. Is expressed in several structures, including brain; digestive system; hatching gland; immune system; and otic vesicle. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 8

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	8	NC_007119.7 (51629197..51661952, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	8	NC_007119.6 (51648181..51675535, complement)

Chromosome 8 - NC_007119.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Neuropeptide Y rceptors zYb and zYc are expressed during ontogeny.
Title: Developmental expression of NPY/PYY receptors zYb and zYc in zebrafish.

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables G protein-coupled receptor activity	IEA Inferred from Electronic Annotation more info
enables neuropeptide Y receptor activity	IEA Inferred from Electronic Annotation more info
enables neuropeptide binding	IBA Inferred from Biological aspect of Ancestor more info
enables neuropeptide binding	IDA Inferred from Direct Assay more info	PubMed
enables neuropeptide receptor activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within signal transduction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
is_active_in neuron projection	IBA Inferred from Biological aspect of Ancestor more info
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: neuropeptide Y receptor Y8b

Names: neuropeptide Y/peptide YY receptor YB

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_131436.1 → NP_571511.1 neuropeptide Y receptor Y8b

See identical proteins and their annotated locations for NP_571511.1

Status: PROVISIONAL

Source sequence(s)

AF030245

UniProtKB/TrEMBL

B3DHJ7, O57463

Related

ENSDARP00000013426.5, ENSDART00000015833.7

Conserved Domains (2) summary

pfam00001
Location:42 → 308

7tm_1; 7 transmembrane receptor (rhodopsin family)

cl21561
Location:38 → 162

7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007119.7 Reference GRCz11 Primary Assembly

Range

51629197..51661952 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_009304308.4 → XP_009302583.1 neuropeptide Y receptor Y8b isoform X1

See identical proteins and their annotated locations for XP_009302583.1

UniProtKB/TrEMBL

B3DHJ7, O57463

Conserved Domains (2) summary

pfam00001
Location:42 → 308

7tm_1; 7 transmembrane receptor (rhodopsin family)

cl21561
Location:38 → 162

7tm_4; Olfactory receptor