hoxa10b homeobox A10b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: hoxa10bprovided by ZNC
Official Full Name: homeobox A10bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-990415-97
See related: Ensembl:ENSDARG00000031337 AllianceGenome:ZFIN:ZDB-GENE-990415-97
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: z-140; hoxa10; Hoxa-10
Summary: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within regulation of DNA-templated transcription. Predicted to be active in nucleus. Is expressed in several structures, including CNS interneuron; chondroblast; mesenchyme; myoblast; and pectoral fin bud. Orthologous to human HOXA10 (homeobox A10). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 16

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	16	NC_007127.7 (20910075..20913003)
105	previous assembly	GRCz10 (GCF_000002035.5)	16	NC_007127.6 (21103735..21107184)

Chromosome 16 - NC_007127.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: homeobox protein Hox-A10b

Names: homeo box A10b; homeobox gene A-10; hox-A10

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_131155.2 → NP_571230.2 homeobox protein Hox-A10b

Status: VALIDATED

Source sequence(s)

CR392024

UniProtKB/Swiss-Prot

O57357, Q4PRA5, Q8AWY2

UniProtKB/TrEMBL

B3DGC1

Related

ENSDARP00000046765.4, ENSDART00000046766.5

Conserved Domains (1) summary

pfam00046
Location:276 → 329

Homeobox; Homeobox domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007127.7 Reference GRCz11 Primary Assembly

Range

20910075..20913003

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005157954.5 → XP_005158011.1 homeobox protein Hox-A10b isoform X1

UniProtKB/Swiss-Prot

O57357, Q4PRA5, Q8AWY2

UniProtKB/TrEMBL

A0A8M2B4B4, B3DGC1

Conserved Domains (1) summary

pfam00046
Location:275 → 328

Homeobox; Homeobox domain