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    ctdsp1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 [ Danio rerio (zebrafish) ]

    Gene ID: 553744, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ctdsp1provided by ZNC
    Official Full Name
    CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050522-523
    See related
    Ensembl:ENSDARG00000040674 AllianceGenome:ZFIN:ZDB-GENE-050522-523
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fj83f12; im:7141428; wu:fj83f12; zgc:113169
    Summary
    Predicted to enable RNA polymerase II CTD heptapeptide repeat phosphatase activity. Orthologous to human CTDSP1 (CTD small phosphatase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See ctdsp1 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (41690153..41740789)
    105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (41888345..41939633)

    Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene striated muscle enriched protein kinase b Neighboring gene microRNA 732 Neighboring gene microRNA 26a-1 Neighboring gene obscurin like cytoskeletal adaptor 1b Neighboring gene uncharacterized LOC137496416

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Comparative transcriptome profiling of the injured zebrafish and mouse hearts identifies miRNA-dependent repair pathways. Crippa S, et al. Cardiovasc Res, 2016 May 1. PMID 26857418, Free PMC Article
    2. Expression of Protein-Coding Gene Orthologs in Zebrafish and Mouse Inner Ear Non-sensory Supporting Cells. Giffen KP, et al. Front Neurosci, 2019. PMID 31680844, Free PMC Article
    3. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    4. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC113169

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA polymerase II CTD heptapeptide repeat phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables myosin phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1; uncharacterized protein ctdsp1
    XP_009303177.1
    XP_021334687.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007120.7 Reference GRCz11 Primary Assembly

      Range
      41690153..41740789
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009304902.4 → XP_009303177.1  carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform X2

      UniProtKB/TrEMBL
      A0A8M3B5V3, B0S5V5
      Related
      ENSDARP00000090999.4, ENSDART00000100226.5
      Conserved Domains (2) summary
      COG5190
      Location:83 → 258
      FCP1; TFIIF-interacting CTD phosphatase, includes NLI-interacting factor [Transcription]
      TIGR02251
      Location:94 → 252
      HIF-SF_euk; Dullard-like phosphatase domain

    2. XM_021479012.2 → XP_021334687.1  uncharacterized protein ctdsp1 isoform X1

      UniProtKB/TrEMBL
      A0A8M9PT21
      Conserved Domains (1) summary
      TIGR02251
      Location:1051 → 1209
      HIF-SF_euk; Dullard-like phosphatase domain

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001020715.2: Suppressed sequence

      Description
      NM_001020715.2: This RefSeq record was removed by NCBI staff. Contact [email protected] for further information.
    Nucleotide Protein Strain
    Heading Accession and Version

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