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    egfem1 EGF-like and EMI domain containing 1 [ Danio rerio (zebrafish) ]

    Gene ID: 567225, updated on 9-Dec-2024

    Summary

    Official Symbol
    egfem1provided by ZNC
    Official Full Name
    EGF-like and EMI domain containing 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-070112-1202
    See related
    AllianceGenome:ZFIN:ZDB-GENE-070112-1202
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    megf6; zgc:158328
    Summary
    Predicted to enable calcium ion binding activity. Predicted to be involved in animal organ development. Orthologous to human MEGF6 (multiple EGF like domains 6). [provided by Alliance of Genome Resources, Dec 2024]
    Annotation information
    Annotation category: partial on reference assembly
    Orthologs
    NEW
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    Genomic context

    See egfem1 in Genome Data Viewer
    Location:
    chromosome: 15
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 15 NC_007126.7 (35253371..35345485)
    105 previous assembly GRCz10 (GCF_000002035.5) 15 NC_007126.6 (35395402..35487516)

    Chromosome 15 - NC_007126.7Genomic Context describing neighboring genes Neighboring gene mitochondrial ribosomal protein L44 Neighboring gene mitochondrial fission factor a Neighboring gene MDS1 and EVI1 complex locus Neighboring gene uncharacterized LOC137487772

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in animal organ development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in biological_process ND
    No biological Data available
    more info
     

    General protein information

    Preferred Names
    EGF-like and EMI domain containing 1
    Names
    EGF-like-domain, multiple 3
    multiple EGF like domains 6

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001080189.1NP_001073658.1  EGF-like and EMI domain containing 1

      See identical proteins and their annotated locations for NP_001073658.1

      Status: PROVISIONAL

      Source sequence(s)
      BC129204
      UniProtKB/TrEMBL
      A1L1T4
      Conserved Domains (3) summary
      pfam07546
      Location:1583
      EMI; EMI domain
      pfam14670
      Location:345380
      FXa_inhibition; Coagulation Factor Xa inhibitory site
      cl00057
      Location:159209
      vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007126.7 Reference GRCz11 Primary Assembly

      Range
      35253371..35345485
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)