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    zgc:158846 zgc:158846 [ Danio rerio (zebrafish) ]

    Gene ID: 100009654, updated on 9-Dec-2024

    Summary

    Official Symbol
    zgc:158846provided by ZNC
    Official Full Name
    zgc:158846provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-070209-50
    See related
    Ensembl:ENSDARG00000058462 AllianceGenome:ZFIN:ZDB-GENE-070209-50
    Gene type
    protein coding
    RefSeq status
    PREDICTED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fb58f07
    Summary
    Predicted to be a structural constituent of skin epidermis. Predicted to be involved in intermediate filament organization and keratinization. Predicted to be located in intermediate filament. Predicted to be active in keratin filament. Human ortholog(s) of this gene implicated in autosomal dominant woolly hair; ectodermal dysplasia 7; hypotrichosis 13; hypotrichosis 3; and liver cirrhosis. Orthologous to several human genes including KRT8 (keratin 8). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See zgc:158846 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (39336731..39344262, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (39339195..39346726, complement)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene si:dkey-195m11.11 Neighboring gene keratin 4 Neighboring gene si:dkey-195m11.8 Neighboring gene keratin 18b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    enables structural constituent of skin epidermis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in intermediate filament organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in keratinization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in intermediate filament IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in keratin filament IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in keratin filament IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    uncharacterized protein LOC100009654
    Names
    krtt2c6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001083023.1NP_001076492.1  uncharacterized protein LOC100009654

      See identical proteins and their annotated locations for NP_001076492.1

      Status: PREDICTED

      Source sequence(s)
      BC133171
      UniProtKB/TrEMBL
      A2RV44
      Related
      ENSDARP00000094849.3, ENSDART00000104074.4
      Conserved Domains (2) summary
      pfam00038
      Location:75386
      Filament; Intermediate filament protein
      pfam16208
      Location:3072
      Keratin_2_head; Keratin type II head

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      39336731..39344262 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394661.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      203096..210540 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)