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    mad2l1 MAD2 mitotic arrest deficient-like 1 (yeast) [ Danio rerio (zebrafish) ]

    Gene ID: 550434, updated on 9-Dec-2024

    Summary

    Official Symbol
    mad2l1provided by ZNC
    Official Full Name
    MAD2 mitotic arrest deficient-like 1 (yeast)provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030515-3
    See related
    Ensembl:ENSDARG00000004713 AllianceGenome:ZFIN:ZDB-GENE-030515-3
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    cb408; zgc:112133
    Summary
    Predicted to be involved in mitotic spindle assembly checkpoint signaling. Predicted to be active in cytoplasm; kinetochore; and nucleoplasm. Is expressed in several structures, including immature eye; nervous system; neural tube; otic vesicle; and proliferative region. Orthologous to human MAD2L1 (mitotic arrest deficient 2 like 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See mad2l1 in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (57629370..57637769, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (57326930..57335329, complement)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene dopamine receptor D4b Neighboring gene sirtuin 3 Neighboring gene phosphodiesterase 5A, cGMP-specific, b Neighboring gene arylsulfatase family, member J Neighboring gene calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Pathways from PubChem

    General gene information

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    involved_in mitotic spindle assembly checkpoint signaling IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in kinetochore IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    mitotic spindle assembly checkpoint protein MAD2A
    Names
    spindle assembly checkpoint protein Mad2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001017739.1NP_001017739.1  mitotic spindle assembly checkpoint protein MAD2A

      See identical proteins and their annotated locations for NP_001017739.1

      Status: PROVISIONAL

      Source sequence(s)
      BC093212
      UniProtKB/TrEMBL
      Q567E0
      Related
      ENSDARP00000003616.6, ENSDART00000028017.7
      Conserved Domains (1) summary
      pfam02301
      Location:10188
      HORMA; HORMA domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      57629370..57637769 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)