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    pdss1 prenyl (decaprenyl) diphosphate synthase, subunit 1 [ Danio rerio (zebrafish) ]

    Gene ID: 550349, updated on 9-Dec-2024

    Summary

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    Official Symbol
    pdss1provided by ZNC
    Official Full Name
    prenyl (decaprenyl) diphosphate synthase, subunit 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-4430
    See related
    Ensembl:ENSDARG00000017910 AllianceGenome:ZFIN:ZDB-GENE-030131-4430
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    tprt; wu:fc11f12; wu:fd05d05; zgc:112058
    Summary
    Predicted to enable prenyltransferase activity. Predicted to be involved in isoprenoid biosynthetic process and ubiquinone biosynthetic process. Predicted to be part of polyprenyl diphosphate synthase complex. Predicted to be active in mitochondrion. Is expressed in several structures, including alar plate midbrain region; lens placode; musculature system; optic vesicle; and segmental plate. Human ortholog(s) of this gene implicated in primary coenzyme Q10 deficiency 2. Orthologous to human PDSS1 (decaprenyl diphosphate synthase subunit 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See pdss1 in Genome Data Viewer
    Location:
    chromosome: 24
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (6015297..6024461, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (5985968..5995143, complement)

    Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene acyl-CoA binding domain containing 5a Neighboring gene abl-interactor 1a Neighboring gene tripartite motif-containing protein 16-like Neighboring gene finTRIM family, member 61

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Cell-specific transcriptional control of mitochondrial metabolism by TIF1γ drives erythropoiesis. Rossmann MP, et al. Science, 2021 May 14. PMID 33986176, Free PMC Article
    2. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables all-trans-decaprenyl-diphosphate synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables prenyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in isoprenoid biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within isoprenoid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in ubiquinone biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of polyprenyl diphosphate synthase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    all trans-polyprenyl-diphosphate synthase PDSS1
    Names
    trans-prenyltransferase
    NP_001017656.1
    XP_005162562.1
    XP_021325838.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001017656.1 → NP_001017656.1  all trans-polyprenyl-diphosphate synthase PDSS1

      See identical proteins and their annotated locations for NP_001017656.1

      Status: PROVISIONAL

      Source sequence(s)
      BC093175
      UniProtKB/TrEMBL
      A0A8M1N5E6, Q567H1
      Related
      ENSDARP00000040864.5, ENSDART00000040865.6
      Conserved Domains (2) summary
      PLN02890
      Location:26 → 411
      PLN02890; geranyl diphosphate synthase
      cl00210
      Location:92 → 409
      Isoprenoid_Biosyn_C1; Isoprenoid Biosynthesis enzymes, Class 1

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007135.7 Reference GRCz11 Primary Assembly

      Range
      6015297..6024461 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005162505.4 → XP_005162562.1  all trans-polyprenyl-diphosphate synthase PDSS1 isoform X1

      UniProtKB/TrEMBL
      A0A8M2B9D7
      Conserved Domains (2) summary
      PLN02890
      Location:26 → 410
      PLN02890; geranyl diphosphate synthase
      cl00210
      Location:92 → 408
      Isoprenoid_Biosyn_C1; Isoprenoid Biosynthesis enzymes, Class 1

    2. XM_021470163.2 → XP_021325838.1  all trans-polyprenyl-diphosphate synthase PDSS1 isoform X2

      UniProtKB/TrEMBL
      A0A8M9PFZ8
      Conserved Domains (1) summary
      cl00210
      Location:57 → 374
      Isoprenoid_Biosyn_C1; Isoprenoid Biosynthesis enzymes, Class 1
    Nucleotide Protein Strain
    Heading Accession and Version

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