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    NIR1 nitrite reductase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 816055, updated on 18-Sep-2024

    Summary

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    Official Symbol
    NIR1
    Official Full Name
    nitrite reductase 1
    Primary source
    TAIR:AT2G15620
    Locus tag
    AT2G15620
    See related
    Araport:AT2G15620
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA NITRITE REDUCTASE; ATHNIR; NIR; NITRITE REDUCTASE; nitrite reductase 1
    Summary
    Involved in the second step of nitrate assimilation. Its expression is induced by nitrate.
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    Genomic context

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    See NIR1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    4
    Sequence:
    Chromosome: 2; NC_003071.7 (6810395..6812941)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene pseudo Neighboring gene hypothetical protein (DUF1685) Neighboring gene Pentatricopeptide repeat (PPR) superfamily protein Neighboring gene F-box family protein Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Nitrite Reductase 1 Is a Target of Nitric Oxide-Mediated Post-Translational Modifications and Controls Nitrogen Flux and Growth in Arabidopsis. Costa-Broseta Á, et al. Int J Mol Sci, 2020 Oct 1. PMID 33019636, Free PMC Article
    2. Nucleotide sequence of a gene for nitrite reductase from Arabidopsis thaliana. Tanaka T, et al. DNA Seq, 1994. PMID 7894060
    3. Identification of a nitrate-responsive cis-element in the Arabidopsis NIR1 promoter defines the presence of multiple cis-regulatory elements for nitrogen response. Konishi M, et al. Plant J, 2010 Jul. PMID 20444232
    4. HY5 regulates nitrite reductase 1 (NIR1) and ammonium transporter1;2 (AMT1;2) in Arabidopsis seedlings. Huang L, et al. Plant Sci, 2015 Sep. PMID 26259199, Free PMC Article
    5. Natural variation in Arabidopsis adaptation to growth at low nitrogen conditions. North KA, et al. Plant Physiol Biochem, 2009 Oct. PMID 19628403

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Nitrite Reductase 1 Is a Target of Nitric Oxide-Mediated Post-Translational Modifications and Controls Nitrogen Flux and Growth in Arabidopsis.
      Title: Nitrite Reductase 1 Is a Target of Nitric Oxide-Mediated Post-Translational Modifications and Controls Nitrogen Flux and Growth in Arabidopsis.
    2. HY5 positively regulates nitrite reductase gene NIR1 and negatively regulates the ammonium transporter gene AMT1;2 under all nitrogen and light conditions tested.
      Title: HY5 regulates nitrite reductase 1 (NIR1) and ammonium transporter1;2 (AMT1;2) in Arabidopsis seedlings.
    3. The NIR1 promoter contains a cis-element is specifically involved in nitrate signaling but not in feedback repression.
      Title: Identification of a nitrate-responsive cis-element in the Arabidopsis NIR1 promoter defines the presence of multiple cis-regulatory elements for nitrogen response.
    4. Data show that in low N conditions the transcripts of the major high affinity transporter NRT2.1 and two genes involved in nitrate reduction, Nia1 for NR and nitrite reductase (NiR), were lower.
      Title: Natural variation in Arabidopsis adaptation to growth at low nitrogen conditions.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_127123.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ferredoxin-nitrite reductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables heme binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nitrite reductase (NO-forming) activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in nitrate assimilation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within response to nitrate IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in apoplast HDA PubMed 
    located_in chloroplast HDA PubMed 
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in chloroplast stroma HDA PubMed 
    NOT located_in cytosol RCA
    inferred from Reviewed Computational Analysis
    more info
    		 PubMed 
    located_in mitochondrion HDA PubMed 

    General protein information

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    Preferred Names
    nitrite reductase 1
    NP_179164.1
    • nitrite reductase 1 (NIR1); FUNCTIONS IN: ferredoxin-nitrate reductase activity, nitrite reductase (NO-forming) activity; INVOLVED IN: response to salt stress, response to nitrate; LOCATED IN: mitochondrion, apoplast, chloroplast stroma, chloroplast, membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Nitrite/sulphite reductase iron-sulphur/siroheam-binding site (InterPro:IPR006066), Nitrite/sulphite reductase 4Fe-4S domain (InterPro:IPR006067), Nitrite/sulphite reductase, hemoprotein beta-component, ferrodoxin-like (InterPro:IPR005117); BEST Arabidopsis thaliana protein match is: sulfite reductase (TAIR:AT5G04590.1); Has 5959 Blast hits to 5874 proteins in 1733 species: Archae - 294; Bacteria - 4692; Metazoa - 2; Fungi - 157; Plants - 240; Viruses - 0; Other Eukaryotes - 574 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      6810395..6812941
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_127123.3 → NP_179164.1  nitrite reductase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_179164.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q39161, Q8H163, Q8H164
      UniProtKB/TrEMBL
      A0A5S9WYB4, A0A654ET38
      Conserved Domains (1) summary
      PLN02431
      Location:1 → 580
      PLN02431; ferredoxin--nitrite reductase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q39161.1

    Gene LinkOut

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