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    tbc1d12a TBC1 domain family, member 12a [ Danio rerio (zebrafish) ]

    Gene ID: 563626, updated on 9-Dec-2024

    Summary

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    Official Symbol
    tbc1d12aprovided by ZNC
    Official Full Name
    TBC1 domain family, member 12aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-3920
    See related
    AllianceGenome:ZFIN:ZDB-GENE-030131-3920
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fc59a02
    Summary
    Predicted to enable GTPase activator activity. Predicted to be involved in regulation of autophagosome assembly. Predicted to be active in autophagosome and recycling endosome. Orthologous to human TBC1D12 (TBC1 domain family member 12). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See tbc1d12a in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (23236125..23255095, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (23216101..23235206, complement)

    Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene si:ch211-195b21.5 Neighboring gene family with sequence similarity 98 member A Neighboring gene D(1)-like dopamine receptor Neighboring gene uncharacterized LOC110439024 Neighboring gene fibroblast growth factor binding protein 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Evolution and expression of the phosphodiesterase 6 genes unveils vertebrate novelty to control photosensitivity. Lagman D, et al. BMC Evol Biol, 2016 Jun 13. PMID 27296292, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    TBC1 domain family member 12

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007128.7 Reference GRCz11 Primary Assembly

      Range
      23236125..23255095 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_686988.10 → XP_692080.2  TBC1 domain family member 12

      UniProtKB/TrEMBL
      A0A8M9PFQ4
      Conserved Domains (1) summary
      smart00164
      Location:519 → 752
      TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394988.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      259942..278920 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021473152.2 → XP_021328827.2  TBC1 domain family member 12

    Reference GRCz11 ALT_DRER_TU_2

    Genomic

    1. NW_018395330.1 Reference GRCz11 ALT_DRER_TU_2

      Range
      136017..154987 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021474367.2 → XP_021330042.1  TBC1 domain family member 12

      UniProtKB/TrEMBL
      A0A8M9PFQ4
      Conserved Domains (1) summary
      smart00164
      Location:519 → 752
      TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
    Nucleotide Protein Strain
    Heading Accession and Version

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